Site-Directed Mutants of Parasporin PS2Aa1 with Enhanced Cytotoxic Activity in Colorectal Cancer Cell Lines
Parasporin 2 has cytotoxic effects against numerous colon cancer cell lines, making it a viable alternative to traditional treatments. However, its mechanism of action and receptors remain unknown. In this study, site-directed mutagenesis was used to obtain PS2Aa1 mutants with variation in domain I...
Main Authors: | Miguel O. Suárez-Barrera, Lydia Visser, Efraín H. Pinzón-Reyes, Paola Rondón Villarreal, Juan S. Alarcón-Aldana, Nohora Juliana Rueda-Forero |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-10-01
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Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/27/21/7262 |
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