COMPARATIVE STUDY ON THE MEASUREMENT OF LIVER T2* VALUES OF THALASSEMIA PATIENTS AND THE CLINICAL GRADING OF LIVER IRON CONCENTRATION BY DIFFERENT POST-PROCESSING SOFTWARE
Objective: To explore the relationship between the liver T2* values of thalassemia patients measured by Circle Cardiovascular Imaging CVI42 (CVI42), CMRtools / Thalassemia Tools (CMRtools) and Excel spreadsheet (Excel), and the three software's accuracy in clinical grading of liver iron concen...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Mattioli1885
2022-10-01
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| Series: | Mediterranean Journal of Hematology and Infectious Diseases |
| Subjects: | |
| Online Access: | https://www.mjhid.org/index.php/mjhid/article/view/5033 |
| _version_ | 1811247897687097344 |
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| author | Peng Peng Fengming XU Jixing YI Bumin LIANG Cheng TANG Qing FENG |
| author_facet | Peng Peng Fengming XU Jixing YI Bumin LIANG Cheng TANG Qing FENG |
| author_sort | Peng Peng |
| collection | DOAJ |
| description |
Objective: To explore the relationship between the liver T2* values of thalassemia patients measured by Circle Cardiovascular Imaging CVI42 (CVI42), CMRtools / Thalassemia Tools (CMRtools) and Excel spreadsheet (Excel), and the three software's accuracy in clinical grading of liver iron concentration (LIC). Methods: The liver T2* images thalassemia patients were imported into CVI42 and CMRtools to measure the T2* value. And the signal intensity (SI) of the T2* image, measured in the MR scanning equipment, was input into Excel to calculate T2* value. The relationship of the T2* values measured by the above three software were compared. And LIC clinical grading was performed on the three measured T2* value results, and the LIC (LICF) provided by FerriScan was used as the reference standard to compare the accuracy of the three grading results. Results: There was no statistical difference between the T2* values measured by CVI42, CMRtools and Excel (P>0.05), but there was a high degree of consistency between them (P<0.05), and there was a high linear positive correlation between the them (P<0.05). There was no statistical difference between the LIC grading results of CVI42 and CMRtools and the LICF grading results (P>0.05). There is a significant difference between the LIC grading results of Excel and the LICF grading results (P<0.05). Conclusion: The liver T2* values measured by CVI42, CMRtools and Excel are equivalent. However, CVI42 and CMRtools have better diagnostic accuracy for LIC clinical grade, while Excel has worse diagnostic accuracy.
Keywords: THALASSEMIA; lIVER T2 VALUE;
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| first_indexed | 2024-04-12T15:17:36Z |
| format | Article |
| id | doaj.art-7c034037efeb44c98be838b1c0f78037 |
| institution | Directory Open Access Journal |
| issn | 2035-3006 |
| language | English |
| last_indexed | 2024-04-12T15:17:36Z |
| publishDate | 2022-10-01 |
| publisher | Mattioli1885 |
| record_format | Article |
| series | Mediterranean Journal of Hematology and Infectious Diseases |
| spelling | doaj.art-7c034037efeb44c98be838b1c0f780372022-12-22T03:27:34ZengMattioli1885Mediterranean Journal of Hematology and Infectious Diseases2035-30062022-10-01141COMPARATIVE STUDY ON THE MEASUREMENT OF LIVER T2* VALUES OF THALASSEMIA PATIENTS AND THE CLINICAL GRADING OF LIVER IRON CONCENTRATION BY DIFFERENT POST-PROCESSING SOFTWAREPeng Peng0Fengming XUJixing YIBumin LIANGCheng TANGQing FENGa:1:{s:5:"en_US";s:141:"Department of Radiology, The First Affiliated Hospital of Guangxi Medical University, Nanning,530021, Guangxi Zhuang Autonomous Region, China";} Objective: To explore the relationship between the liver T2* values of thalassemia patients measured by Circle Cardiovascular Imaging CVI42 (CVI42), CMRtools / Thalassemia Tools (CMRtools) and Excel spreadsheet (Excel), and the three software's accuracy in clinical grading of liver iron concentration (LIC). Methods: The liver T2* images thalassemia patients were imported into CVI42 and CMRtools to measure the T2* value. And the signal intensity (SI) of the T2* image, measured in the MR scanning equipment, was input into Excel to calculate T2* value. The relationship of the T2* values measured by the above three software were compared. And LIC clinical grading was performed on the three measured T2* value results, and the LIC (LICF) provided by FerriScan was used as the reference standard to compare the accuracy of the three grading results. Results: There was no statistical difference between the T2* values measured by CVI42, CMRtools and Excel (P>0.05), but there was a high degree of consistency between them (P<0.05), and there was a high linear positive correlation between the them (P<0.05). There was no statistical difference between the LIC grading results of CVI42 and CMRtools and the LICF grading results (P>0.05). There is a significant difference between the LIC grading results of Excel and the LICF grading results (P<0.05). Conclusion: The liver T2* values measured by CVI42, CMRtools and Excel are equivalent. However, CVI42 and CMRtools have better diagnostic accuracy for LIC clinical grade, while Excel has worse diagnostic accuracy. Keywords: THALASSEMIA; lIVER T2 VALUE; https://www.mjhid.org/index.php/mjhid/article/view/5033Thalassemia; liver iron concentration; comparative study; iron overload |
| spellingShingle | Peng Peng Fengming XU Jixing YI Bumin LIANG Cheng TANG Qing FENG COMPARATIVE STUDY ON THE MEASUREMENT OF LIVER T2* VALUES OF THALASSEMIA PATIENTS AND THE CLINICAL GRADING OF LIVER IRON CONCENTRATION BY DIFFERENT POST-PROCESSING SOFTWARE Mediterranean Journal of Hematology and Infectious Diseases Thalassemia; liver iron concentration; comparative study; iron overload |
| title | COMPARATIVE STUDY ON THE MEASUREMENT OF LIVER T2* VALUES OF THALASSEMIA PATIENTS AND THE CLINICAL GRADING OF LIVER IRON CONCENTRATION BY DIFFERENT POST-PROCESSING SOFTWARE |
| title_full | COMPARATIVE STUDY ON THE MEASUREMENT OF LIVER T2* VALUES OF THALASSEMIA PATIENTS AND THE CLINICAL GRADING OF LIVER IRON CONCENTRATION BY DIFFERENT POST-PROCESSING SOFTWARE |
| title_fullStr | COMPARATIVE STUDY ON THE MEASUREMENT OF LIVER T2* VALUES OF THALASSEMIA PATIENTS AND THE CLINICAL GRADING OF LIVER IRON CONCENTRATION BY DIFFERENT POST-PROCESSING SOFTWARE |
| title_full_unstemmed | COMPARATIVE STUDY ON THE MEASUREMENT OF LIVER T2* VALUES OF THALASSEMIA PATIENTS AND THE CLINICAL GRADING OF LIVER IRON CONCENTRATION BY DIFFERENT POST-PROCESSING SOFTWARE |
| title_short | COMPARATIVE STUDY ON THE MEASUREMENT OF LIVER T2* VALUES OF THALASSEMIA PATIENTS AND THE CLINICAL GRADING OF LIVER IRON CONCENTRATION BY DIFFERENT POST-PROCESSING SOFTWARE |
| title_sort | comparative study on the measurement of liver t2 values of thalassemia patients and the clinical grading of liver iron concentration by different post processing software |
| topic | Thalassemia; liver iron concentration; comparative study; iron overload |
| url | https://www.mjhid.org/index.php/mjhid/article/view/5033 |
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