Biotransfer of β-N-Methylamino-l-alanine (BMAA) in a Eutrophicated Freshwater Lake
β-N-Methylamino-l-alanine (BMAA), a neurotoxic non-protein amino acid, plays a significant role as an environmental risk factor in neurodegenerative diseases, such as amyotrophic lateral sclerosis. BMAA producers occur globally, colonizing almost all habitats and represent species from distinct phyt...
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| Format: | Article |
| Language: | English |
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MDPI AG
2015-03-01
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| Series: | Marine Drugs |
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| Online Access: | http://www.mdpi.com/1660-3397/13/3/1185 |
| _version_ | 1811277993037791232 |
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| author | Sandra Lage Heléne Annadotter Ulla Rasmussen Sara Rydberg |
| author_facet | Sandra Lage Heléne Annadotter Ulla Rasmussen Sara Rydberg |
| author_sort | Sandra Lage |
| collection | DOAJ |
| description | β-N-Methylamino-l-alanine (BMAA), a neurotoxic non-protein amino acid, plays a significant role as an environmental risk factor in neurodegenerative diseases, such as amyotrophic lateral sclerosis. BMAA producers occur globally, colonizing almost all habitats and represent species from distinct phytoplanktonic groups, i.e., cyanobacteria, diatoms, and dinoflagellates. Bioaccumulation of BMAA in invertebrate and vertebrate organisms has also been registered around the globe. In the Baltic Sea, BMAA has been detected in several commercial fish species, raising the question of the bioaccumulation of BMAA in Swedish limnic systems. Here we find the presence of BMAA in water samples from Lake Finjasjön and identify its bioaccumulation patterns in both plankti-benthivorous and piscivorous fish, according to fish species, total weight, gender, and season of collection. For the first time, a large number of fish individuals were used in order to draw conclusions on BMAA bioaccumulation in a closed ecological community based on a statistical approach. We may, therefore, conclude that feeding patterns (plankti-benthivorous) and increased age of fish may lead to a higher tissue concentration of BMAA. |
| first_indexed | 2024-04-13T00:27:54Z |
| format | Article |
| id | doaj.art-7c05c6a8b8a84acdb163e49a478a0f89 |
| institution | Directory Open Access Journal |
| issn | 1660-3397 |
| language | English |
| last_indexed | 2024-04-13T00:27:54Z |
| publishDate | 2015-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Marine Drugs |
| spelling | doaj.art-7c05c6a8b8a84acdb163e49a478a0f892022-12-22T03:10:34ZengMDPI AGMarine Drugs1660-33972015-03-011331185120110.3390/md13031185md13031185Biotransfer of β-N-Methylamino-l-alanine (BMAA) in a Eutrophicated Freshwater LakeSandra Lage0Heléne Annadotter1Ulla Rasmussen2Sara Rydberg3Department of Ecology, Environment and Plant Sciences, Stockholm University, 10654 Stockholm, SwedenRegito AB, 28022 Vittsjö, SwedenDepartment of Ecology, Environment and Plant Sciences, Stockholm University, 10654 Stockholm, SwedenDepartment of Ecology, Environment and Plant Sciences, Stockholm University, 10654 Stockholm, Swedenβ-N-Methylamino-l-alanine (BMAA), a neurotoxic non-protein amino acid, plays a significant role as an environmental risk factor in neurodegenerative diseases, such as amyotrophic lateral sclerosis. BMAA producers occur globally, colonizing almost all habitats and represent species from distinct phytoplanktonic groups, i.e., cyanobacteria, diatoms, and dinoflagellates. Bioaccumulation of BMAA in invertebrate and vertebrate organisms has also been registered around the globe. In the Baltic Sea, BMAA has been detected in several commercial fish species, raising the question of the bioaccumulation of BMAA in Swedish limnic systems. Here we find the presence of BMAA in water samples from Lake Finjasjön and identify its bioaccumulation patterns in both plankti-benthivorous and piscivorous fish, according to fish species, total weight, gender, and season of collection. For the first time, a large number of fish individuals were used in order to draw conclusions on BMAA bioaccumulation in a closed ecological community based on a statistical approach. We may, therefore, conclude that feeding patterns (plankti-benthivorous) and increased age of fish may lead to a higher tissue concentration of BMAA.http://www.mdpi.com/1660-3397/13/3/1185Lake Finjasjönβ-N-methylamino-l-alaninebioaccumulationphytoplanktonfish |
| spellingShingle | Sandra Lage Heléne Annadotter Ulla Rasmussen Sara Rydberg Biotransfer of β-N-Methylamino-l-alanine (BMAA) in a Eutrophicated Freshwater Lake Marine Drugs Lake Finjasjön β-N-methylamino-l-alanine bioaccumulation phytoplankton fish |
| title | Biotransfer of β-N-Methylamino-l-alanine (BMAA) in a Eutrophicated Freshwater Lake |
| title_full | Biotransfer of β-N-Methylamino-l-alanine (BMAA) in a Eutrophicated Freshwater Lake |
| title_fullStr | Biotransfer of β-N-Methylamino-l-alanine (BMAA) in a Eutrophicated Freshwater Lake |
| title_full_unstemmed | Biotransfer of β-N-Methylamino-l-alanine (BMAA) in a Eutrophicated Freshwater Lake |
| title_short | Biotransfer of β-N-Methylamino-l-alanine (BMAA) in a Eutrophicated Freshwater Lake |
| title_sort | biotransfer of β n methylamino l alanine bmaa in a eutrophicated freshwater lake |
| topic | Lake Finjasjön β-N-methylamino-l-alanine bioaccumulation phytoplankton fish |
| url | http://www.mdpi.com/1660-3397/13/3/1185 |
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