Custom-made 3D printed subperiosteal titanium implants for the prosthetic restoration of the atrophic posterior mandible of elderly patients: a case series

Abstract Purpose To present the application of custom-made 3D-printed subperiosteal implants for fixed prosthetic restoration of the atrophic posterior mandible of elderly patients. Methods Between January 2017 and June 2018, all partially edentulous patients aged over 65 years, with two or more mis...

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Main Authors: Carlo Mangano, Andrea Bianchi, Francesco Guido Mangano, Jessica Dana, Marco Colombo, Ivan Solop, Oleg Admakin
Format: Article
Language:English
Published: BMC 2020-01-01
Series:3D Printing in Medicine
Subjects:
Online Access:https://doi.org/10.1186/s41205-019-0055-x
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author Carlo Mangano
Andrea Bianchi
Francesco Guido Mangano
Jessica Dana
Marco Colombo
Ivan Solop
Oleg Admakin
author_facet Carlo Mangano
Andrea Bianchi
Francesco Guido Mangano
Jessica Dana
Marco Colombo
Ivan Solop
Oleg Admakin
author_sort Carlo Mangano
collection DOAJ
description Abstract Purpose To present the application of custom-made 3D-printed subperiosteal implants for fixed prosthetic restoration of the atrophic posterior mandible of elderly patients. Methods Between January 2017 and June 2018, all partially edentulous patients aged over 65 years, with two or more missing teeth in the posterior atrophic mandible, and who did not want to undergo bone regenerative procedures, were included in this study. These patients were rehabilitated with custom-made subperiosteal implants, designed from cone beam computed tomography (CBCT) and fabricated in titanium by means of direct metal laser sintering (DMLS). The outcome measures were fit and stability of the implants at placement, duration of the intervention, implant survival, and early and late complications. All patients were followed for 1 year after surgery. Results Ten patients (four males, six females; mean age 69.6, SD ± 2.8, median 69, 95% CI 67.9–71.6) were included in the study. The fit of the implants was satisfactory, with a mean rating of 7 out of 10 (SD ± 1.6, median 7, 95% CI 6–8). Only two implants had insufficient fit, because of the presence of scattering in the CBCT; however, they were adapted to the sites during the interventions. The mean duration of the intervention was 44.3 min (SD ± 19.4, median 37, 95% CI 32.3–56.3). At the one-year follow-up, no implants were lost (survival rate 100%). One implant presented immediate postoperative complications with pain, discomfort and swelling, and two patients experienced late complications, having their provisional restorations fractured during the temporisation phase. All these complications were minor in nature, but the final complication rate amounted to 30% (three of ten patients). Conclusions Although this study has limits (small patient sample and short follow-up), DMLS has proven to be an effective method for fabricating accurate subperiosteal implants, with high survival rates. This may represent an alternative treatment procedure in elderly patients with a severely atrophic posterior mandible, since it allows avoidance of regenerative bone therapies. Further studies are needed to confirm these outcomes.
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spelling doaj.art-7c06863db94445b1ab156bd75ffd1ef62022-12-21T23:23:00ZengBMC3D Printing in Medicine2365-62712020-01-016111410.1186/s41205-019-0055-xCustom-made 3D printed subperiosteal titanium implants for the prosthetic restoration of the atrophic posterior mandible of elderly patients: a case seriesCarlo Mangano0Andrea Bianchi1Francesco Guido Mangano2Jessica Dana3Marco Colombo4Ivan Solop5Oleg Admakin6Department of Dental Sciences, University Vita Salute S. RaffaeleDepartment of Periodontology and Implantology, Istituto Stomatologico ItalianoDepartment of Prevention and Communal Dentistry, Sechenov First Moscow State Medical UniversityPrivate PracticePrivate PracticeDepartment of Prevention and Communal Dentistry, Sechenov First Moscow State Medical UniversityDepartment of Prevention and Communal Dentistry, Sechenov First Moscow State Medical UniversityAbstract Purpose To present the application of custom-made 3D-printed subperiosteal implants for fixed prosthetic restoration of the atrophic posterior mandible of elderly patients. Methods Between January 2017 and June 2018, all partially edentulous patients aged over 65 years, with two or more missing teeth in the posterior atrophic mandible, and who did not want to undergo bone regenerative procedures, were included in this study. These patients were rehabilitated with custom-made subperiosteal implants, designed from cone beam computed tomography (CBCT) and fabricated in titanium by means of direct metal laser sintering (DMLS). The outcome measures were fit and stability of the implants at placement, duration of the intervention, implant survival, and early and late complications. All patients were followed for 1 year after surgery. Results Ten patients (four males, six females; mean age 69.6, SD ± 2.8, median 69, 95% CI 67.9–71.6) were included in the study. The fit of the implants was satisfactory, with a mean rating of 7 out of 10 (SD ± 1.6, median 7, 95% CI 6–8). Only two implants had insufficient fit, because of the presence of scattering in the CBCT; however, they were adapted to the sites during the interventions. The mean duration of the intervention was 44.3 min (SD ± 19.4, median 37, 95% CI 32.3–56.3). At the one-year follow-up, no implants were lost (survival rate 100%). One implant presented immediate postoperative complications with pain, discomfort and swelling, and two patients experienced late complications, having their provisional restorations fractured during the temporisation phase. All these complications were minor in nature, but the final complication rate amounted to 30% (three of ten patients). Conclusions Although this study has limits (small patient sample and short follow-up), DMLS has proven to be an effective method for fabricating accurate subperiosteal implants, with high survival rates. This may represent an alternative treatment procedure in elderly patients with a severely atrophic posterior mandible, since it allows avoidance of regenerative bone therapies. Further studies are needed to confirm these outcomes.https://doi.org/10.1186/s41205-019-0055-xCustom-madeSubperiosteal implantsDirect metal laser sintering (DMLS)Atrophic posterior mandibleElderly patients
spellingShingle Carlo Mangano
Andrea Bianchi
Francesco Guido Mangano
Jessica Dana
Marco Colombo
Ivan Solop
Oleg Admakin
Custom-made 3D printed subperiosteal titanium implants for the prosthetic restoration of the atrophic posterior mandible of elderly patients: a case series
3D Printing in Medicine
Custom-made
Subperiosteal implants
Direct metal laser sintering (DMLS)
Atrophic posterior mandible
Elderly patients
title Custom-made 3D printed subperiosteal titanium implants for the prosthetic restoration of the atrophic posterior mandible of elderly patients: a case series
title_full Custom-made 3D printed subperiosteal titanium implants for the prosthetic restoration of the atrophic posterior mandible of elderly patients: a case series
title_fullStr Custom-made 3D printed subperiosteal titanium implants for the prosthetic restoration of the atrophic posterior mandible of elderly patients: a case series
title_full_unstemmed Custom-made 3D printed subperiosteal titanium implants for the prosthetic restoration of the atrophic posterior mandible of elderly patients: a case series
title_short Custom-made 3D printed subperiosteal titanium implants for the prosthetic restoration of the atrophic posterior mandible of elderly patients: a case series
title_sort custom made 3d printed subperiosteal titanium implants for the prosthetic restoration of the atrophic posterior mandible of elderly patients a case series
topic Custom-made
Subperiosteal implants
Direct metal laser sintering (DMLS)
Atrophic posterior mandible
Elderly patients
url https://doi.org/10.1186/s41205-019-0055-x
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