Dietary antioxidants and vascular calcification: From pharmacological mechanisms to challenges
Vascular calcification (VC), an actively regulated process, has been recognized as an independent and strong predictor of cardiovascular disease (CVD) and mortality worldwide. Diet has been shown to have a major role in the progression of VC. Oxidative stress (OS), a common pro-calcification factor,...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-12-01
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| Series: | Biomedicine & Pharmacotherapy |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0753332223014919 |
| _version_ | 1797630684732325888 |
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| author | Yaxin Lian Yue Li Aiting Liu Sounak Ghosh Yuncong Shi Hui Huang |
| author_facet | Yaxin Lian Yue Li Aiting Liu Sounak Ghosh Yuncong Shi Hui Huang |
| author_sort | Yaxin Lian |
| collection | DOAJ |
| description | Vascular calcification (VC), an actively regulated process, has been recognized as an independent and strong predictor of cardiovascular disease (CVD) and mortality worldwide. Diet has been shown to have a major role in the progression of VC. Oxidative stress (OS), a common pro-calcification factor, is closely related to VC, and evidence strongly suggests that dietary antioxidants directly prevent VC. Herein, we provided an overview of OS and its key role in VC and underlined the mechanisms of harmful effects of OS on VC. Furthermore, we introduced dietary antioxidants, and discussed about surrounding the challenges of dietary antioxidants in VC management. This review will benefit future research about the effects of dietary antioxidants on cardiovascular health. |
| first_indexed | 2024-03-11T11:10:38Z |
| format | Article |
| id | doaj.art-7c0893ecf476472495dcefec650cb3bd |
| institution | Directory Open Access Journal |
| issn | 0753-3322 |
| language | English |
| last_indexed | 2024-03-11T11:10:38Z |
| publishDate | 2023-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Biomedicine & Pharmacotherapy |
| spelling | doaj.art-7c0893ecf476472495dcefec650cb3bd2023-11-12T04:38:56ZengElsevierBiomedicine & Pharmacotherapy0753-33222023-12-01168115693Dietary antioxidants and vascular calcification: From pharmacological mechanisms to challengesYaxin Lian0Yue Li1Aiting Liu2Sounak Ghosh3Yuncong Shi4Hui Huang5The Eighth Affiliated Hospital, Sun Yat-sen University, No. 3025, Shennan Middle Rd, Futian District, 518033 Shenzhen, ChinaThe Eighth Affiliated Hospital, Sun Yat-sen University, No. 3025, Shennan Middle Rd, Futian District, 518033 Shenzhen, ChinaThe Eighth Affiliated Hospital, Sun Yat-sen University, No. 3025, Shennan Middle Rd, Futian District, 518033 Shenzhen, ChinaDepartment of Internal Medicine, AMRI Hospital, Kolkata, IndiaThe Eighth Affiliated Hospital, Sun Yat-sen University, No. 3025, Shennan Middle Rd, Futian District, 518033 Shenzhen, ChinaThe Eighth Affiliated Hospital, Sun Yat-sen University, No. 3025, Shennan Middle Rd, Futian District, 518033 Shenzhen, China; Corresponding author.Vascular calcification (VC), an actively regulated process, has been recognized as an independent and strong predictor of cardiovascular disease (CVD) and mortality worldwide. Diet has been shown to have a major role in the progression of VC. Oxidative stress (OS), a common pro-calcification factor, is closely related to VC, and evidence strongly suggests that dietary antioxidants directly prevent VC. Herein, we provided an overview of OS and its key role in VC and underlined the mechanisms of harmful effects of OS on VC. Furthermore, we introduced dietary antioxidants, and discussed about surrounding the challenges of dietary antioxidants in VC management. This review will benefit future research about the effects of dietary antioxidants on cardiovascular health.http://www.sciencedirect.com/science/article/pii/S0753332223014919Dietary antioxidantsVascular calcificationOxidative stressCardiovascular disease |
| spellingShingle | Yaxin Lian Yue Li Aiting Liu Sounak Ghosh Yuncong Shi Hui Huang Dietary antioxidants and vascular calcification: From pharmacological mechanisms to challenges Biomedicine & Pharmacotherapy Dietary antioxidants Vascular calcification Oxidative stress Cardiovascular disease |
| title | Dietary antioxidants and vascular calcification: From pharmacological mechanisms to challenges |
| title_full | Dietary antioxidants and vascular calcification: From pharmacological mechanisms to challenges |
| title_fullStr | Dietary antioxidants and vascular calcification: From pharmacological mechanisms to challenges |
| title_full_unstemmed | Dietary antioxidants and vascular calcification: From pharmacological mechanisms to challenges |
| title_short | Dietary antioxidants and vascular calcification: From pharmacological mechanisms to challenges |
| title_sort | dietary antioxidants and vascular calcification from pharmacological mechanisms to challenges |
| topic | Dietary antioxidants Vascular calcification Oxidative stress Cardiovascular disease |
| url | http://www.sciencedirect.com/science/article/pii/S0753332223014919 |
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