Role of Biomarkers in the Diagnosis, Risk Assessment, and Management of Pulmonary Hypertension
Pulmonary hypertension is a severe and debilitating disease with no definite cure, and the domain of targeted therapies is a promising field for better management of this severe condition. The disease comprises pulmonary arterial remodeling, hypoxia, endothelial dysfunction, and inflammation, with s...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2016-01-01
|
Series: | Biomarker Insights |
Online Access: | https://doi.org/10.4137/BMI.S38323 |
_version_ | 1818399153252728832 |
---|---|
author | Vanessa Rameh Antoine Kossaify |
author_facet | Vanessa Rameh Antoine Kossaify |
author_sort | Vanessa Rameh |
collection | DOAJ |
description | Pulmonary hypertension is a severe and debilitating disease with no definite cure, and the domain of targeted therapies is a promising field for better management of this severe condition. The disease comprises pulmonary arterial remodeling, hypoxia, endothelial dysfunction, and inflammation, with subsequent organ damage including right heart and liver dysfunction. Biomarkers have a valuable role at different levels of the disease, from diagnosis to risk assessment and management, in order to decrease the burden of the disease in terms of both morbidity and mortality. |
first_indexed | 2024-12-14T07:16:09Z |
format | Article |
id | doaj.art-7c0d87cfc668488291b9f4612476cda5 |
institution | Directory Open Access Journal |
issn | 1177-2719 |
language | English |
last_indexed | 2024-12-14T07:16:09Z |
publishDate | 2016-01-01 |
publisher | SAGE Publishing |
record_format | Article |
series | Biomarker Insights |
spelling | doaj.art-7c0d87cfc668488291b9f4612476cda52022-12-21T23:11:43ZengSAGE PublishingBiomarker Insights1177-27192016-01-011110.4137/BMI.S38323Role of Biomarkers in the Diagnosis, Risk Assessment, and Management of Pulmonary HypertensionVanessa Rameh0Antoine Kossaify1Echocardiography Unit, Cardiology division, University Hospital Notre Dame des Secours, Byblos, Lebanon.Echocardiography Unit, Cardiology division, University Hospital Notre Dame des Secours, Byblos, Lebanon.Pulmonary hypertension is a severe and debilitating disease with no definite cure, and the domain of targeted therapies is a promising field for better management of this severe condition. The disease comprises pulmonary arterial remodeling, hypoxia, endothelial dysfunction, and inflammation, with subsequent organ damage including right heart and liver dysfunction. Biomarkers have a valuable role at different levels of the disease, from diagnosis to risk assessment and management, in order to decrease the burden of the disease in terms of both morbidity and mortality.https://doi.org/10.4137/BMI.S38323 |
spellingShingle | Vanessa Rameh Antoine Kossaify Role of Biomarkers in the Diagnosis, Risk Assessment, and Management of Pulmonary Hypertension Biomarker Insights |
title | Role of Biomarkers in the Diagnosis, Risk Assessment, and Management of Pulmonary Hypertension |
title_full | Role of Biomarkers in the Diagnosis, Risk Assessment, and Management of Pulmonary Hypertension |
title_fullStr | Role of Biomarkers in the Diagnosis, Risk Assessment, and Management of Pulmonary Hypertension |
title_full_unstemmed | Role of Biomarkers in the Diagnosis, Risk Assessment, and Management of Pulmonary Hypertension |
title_short | Role of Biomarkers in the Diagnosis, Risk Assessment, and Management of Pulmonary Hypertension |
title_sort | role of biomarkers in the diagnosis risk assessment and management of pulmonary hypertension |
url | https://doi.org/10.4137/BMI.S38323 |
work_keys_str_mv | AT vanessarameh roleofbiomarkersinthediagnosisriskassessmentandmanagementofpulmonaryhypertension AT antoinekossaify roleofbiomarkersinthediagnosisriskassessmentandmanagementofpulmonaryhypertension |