Role of Biomarkers in the Diagnosis, Risk Assessment, and Management of Pulmonary Hypertension

Pulmonary hypertension is a severe and debilitating disease with no definite cure, and the domain of targeted therapies is a promising field for better management of this severe condition. The disease comprises pulmonary arterial remodeling, hypoxia, endothelial dysfunction, and inflammation, with s...

Full description

Bibliographic Details
Main Authors: Vanessa Rameh, Antoine Kossaify
Format: Article
Language:English
Published: SAGE Publishing 2016-01-01
Series:Biomarker Insights
Online Access:https://doi.org/10.4137/BMI.S38323
_version_ 1818399153252728832
author Vanessa Rameh
Antoine Kossaify
author_facet Vanessa Rameh
Antoine Kossaify
author_sort Vanessa Rameh
collection DOAJ
description Pulmonary hypertension is a severe and debilitating disease with no definite cure, and the domain of targeted therapies is a promising field for better management of this severe condition. The disease comprises pulmonary arterial remodeling, hypoxia, endothelial dysfunction, and inflammation, with subsequent organ damage including right heart and liver dysfunction. Biomarkers have a valuable role at different levels of the disease, from diagnosis to risk assessment and management, in order to decrease the burden of the disease in terms of both morbidity and mortality.
first_indexed 2024-12-14T07:16:09Z
format Article
id doaj.art-7c0d87cfc668488291b9f4612476cda5
institution Directory Open Access Journal
issn 1177-2719
language English
last_indexed 2024-12-14T07:16:09Z
publishDate 2016-01-01
publisher SAGE Publishing
record_format Article
series Biomarker Insights
spelling doaj.art-7c0d87cfc668488291b9f4612476cda52022-12-21T23:11:43ZengSAGE PublishingBiomarker Insights1177-27192016-01-011110.4137/BMI.S38323Role of Biomarkers in the Diagnosis, Risk Assessment, and Management of Pulmonary HypertensionVanessa Rameh0Antoine Kossaify1Echocardiography Unit, Cardiology division, University Hospital Notre Dame des Secours, Byblos, Lebanon.Echocardiography Unit, Cardiology division, University Hospital Notre Dame des Secours, Byblos, Lebanon.Pulmonary hypertension is a severe and debilitating disease with no definite cure, and the domain of targeted therapies is a promising field for better management of this severe condition. The disease comprises pulmonary arterial remodeling, hypoxia, endothelial dysfunction, and inflammation, with subsequent organ damage including right heart and liver dysfunction. Biomarkers have a valuable role at different levels of the disease, from diagnosis to risk assessment and management, in order to decrease the burden of the disease in terms of both morbidity and mortality.https://doi.org/10.4137/BMI.S38323
spellingShingle Vanessa Rameh
Antoine Kossaify
Role of Biomarkers in the Diagnosis, Risk Assessment, and Management of Pulmonary Hypertension
Biomarker Insights
title Role of Biomarkers in the Diagnosis, Risk Assessment, and Management of Pulmonary Hypertension
title_full Role of Biomarkers in the Diagnosis, Risk Assessment, and Management of Pulmonary Hypertension
title_fullStr Role of Biomarkers in the Diagnosis, Risk Assessment, and Management of Pulmonary Hypertension
title_full_unstemmed Role of Biomarkers in the Diagnosis, Risk Assessment, and Management of Pulmonary Hypertension
title_short Role of Biomarkers in the Diagnosis, Risk Assessment, and Management of Pulmonary Hypertension
title_sort role of biomarkers in the diagnosis risk assessment and management of pulmonary hypertension
url https://doi.org/10.4137/BMI.S38323
work_keys_str_mv AT vanessarameh roleofbiomarkersinthediagnosisriskassessmentandmanagementofpulmonaryhypertension
AT antoinekossaify roleofbiomarkersinthediagnosisriskassessmentandmanagementofpulmonaryhypertension