pH-Responsive Hollow Polymeric Microspheres from Irradiated Cyclic Ether Aqueous Solution
Smart hollow polymeric microspheres have been widely applied in various fields such as controlled release, drug delivery, catalysis, and so on. Herein, a facile, green and one-step template-free method is introduced for preparing pH-responsive hollow polymeric microspheres via gamma irradiation of c...
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MDPI AG
2021-09-01
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| Series: | Applied Sciences |
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| Online Access: | https://www.mdpi.com/2076-3417/11/18/8652 |
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| author | Chuhong Yu Jing Peng Jiuqiang Li Maolin Zhai |
| author_facet | Chuhong Yu Jing Peng Jiuqiang Li Maolin Zhai |
| author_sort | Chuhong Yu |
| collection | DOAJ |
| description | Smart hollow polymeric microspheres have been widely applied in various fields such as controlled release, drug delivery, catalysis, and so on. Herein, a facile, green and one-step template-free method is introduced for preparing pH-responsive hollow polymeric microspheres via gamma irradiation of cyclic ether aqueous solution. The hollow polymeric microspheres are synthesized by radiation-induced polymerization and following the self-assembly and self-organization of amphiphilic polymer with cyclic ethers as monomers in water. SEM, TEM, micro-FTIR, and NMR confirmed the morphology and structures of the resultant microspheres. The confocal laser scanning microscope was used to investigate the stimuli-responsiveness and release behavior of hollow microspheres using 1-pyrene carboxaldehyde as a hydrophobic molecule model. The well-defined hollow polymeric microspheres with an average diameter of ca. 2.6 μm or 1.6 μm were prepared directly from dicyclohexal-18-crown-6 or tetraphydropyrane aqueous solution, respectively. The prepared hollow microspheres exhibit obvious pH stimuli-responsiveness and can release the encapsulated hydrophobic molecules when pH is higher than 5.0. Moreover, the reversible morphology transition between hollow microspheres and micelles makes the prepared hollow polymeric microspheres potentially suitable for a wide range of applications, including removal of dyes, oil field engineering, and biomedical fields. |
| first_indexed | 2024-03-10T07:55:12Z |
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| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-10T07:55:12Z |
| publishDate | 2021-09-01 |
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| spelling | doaj.art-7c0e93fe1b054f149c6244bc0d6f8bf42023-11-22T11:56:09ZengMDPI AGApplied Sciences2076-34172021-09-011118865210.3390/app11188652pH-Responsive Hollow Polymeric Microspheres from Irradiated Cyclic Ether Aqueous SolutionChuhong Yu0Jing Peng1Jiuqiang Li2Maolin Zhai3Beijing National Laboratory for Molecular Sciences, Radiochemistry and Radiation Chemistry Key Laboratory of Fundamental Science, Key Laboratory of Polymer Chemistry and Physics of the Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, ChinaBeijing National Laboratory for Molecular Sciences, Radiochemistry and Radiation Chemistry Key Laboratory of Fundamental Science, Key Laboratory of Polymer Chemistry and Physics of the Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, ChinaBeijing National Laboratory for Molecular Sciences, Radiochemistry and Radiation Chemistry Key Laboratory of Fundamental Science, Key Laboratory of Polymer Chemistry and Physics of the Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, ChinaBeijing National Laboratory for Molecular Sciences, Radiochemistry and Radiation Chemistry Key Laboratory of Fundamental Science, Key Laboratory of Polymer Chemistry and Physics of the Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, ChinaSmart hollow polymeric microspheres have been widely applied in various fields such as controlled release, drug delivery, catalysis, and so on. Herein, a facile, green and one-step template-free method is introduced for preparing pH-responsive hollow polymeric microspheres via gamma irradiation of cyclic ether aqueous solution. The hollow polymeric microspheres are synthesized by radiation-induced polymerization and following the self-assembly and self-organization of amphiphilic polymer with cyclic ethers as monomers in water. SEM, TEM, micro-FTIR, and NMR confirmed the morphology and structures of the resultant microspheres. The confocal laser scanning microscope was used to investigate the stimuli-responsiveness and release behavior of hollow microspheres using 1-pyrene carboxaldehyde as a hydrophobic molecule model. The well-defined hollow polymeric microspheres with an average diameter of ca. 2.6 μm or 1.6 μm were prepared directly from dicyclohexal-18-crown-6 or tetraphydropyrane aqueous solution, respectively. The prepared hollow microspheres exhibit obvious pH stimuli-responsiveness and can release the encapsulated hydrophobic molecules when pH is higher than 5.0. Moreover, the reversible morphology transition between hollow microspheres and micelles makes the prepared hollow polymeric microspheres potentially suitable for a wide range of applications, including removal of dyes, oil field engineering, and biomedical fields.https://www.mdpi.com/2076-3417/11/18/8652γ-irradiationcyclic ethersstimuli-responsivenesshollow microspheres |
| spellingShingle | Chuhong Yu Jing Peng Jiuqiang Li Maolin Zhai pH-Responsive Hollow Polymeric Microspheres from Irradiated Cyclic Ether Aqueous Solution Applied Sciences γ-irradiation cyclic ethers stimuli-responsiveness hollow microspheres |
| title | pH-Responsive Hollow Polymeric Microspheres from Irradiated Cyclic Ether Aqueous Solution |
| title_full | pH-Responsive Hollow Polymeric Microspheres from Irradiated Cyclic Ether Aqueous Solution |
| title_fullStr | pH-Responsive Hollow Polymeric Microspheres from Irradiated Cyclic Ether Aqueous Solution |
| title_full_unstemmed | pH-Responsive Hollow Polymeric Microspheres from Irradiated Cyclic Ether Aqueous Solution |
| title_short | pH-Responsive Hollow Polymeric Microspheres from Irradiated Cyclic Ether Aqueous Solution |
| title_sort | ph responsive hollow polymeric microspheres from irradiated cyclic ether aqueous solution |
| topic | γ-irradiation cyclic ethers stimuli-responsiveness hollow microspheres |
| url | https://www.mdpi.com/2076-3417/11/18/8652 |
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