Diagnostic Ability of Convex-Arrayed Endoscopic Ultrasonography for Major Vascular Invasion in Pancreatic Cancer
Background/Aims This study aimed to examine the diagnostic ability of endoscopic ultrasonography (EUS) for major vascular invasion in pancreatic cancer and to evaluate the relationship between EUS findings and pathological distance. Methods In total, 57 consecutive patients who underwent EUS for pan...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Korean Society of Gastrointestinal Endoscopy
2019-09-01
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| Series: | Clinical Endoscopy |
| Subjects: | |
| Online Access: | http://www.e-ce.org/upload/pdf/ce-2018-163.pdf |
| _version_ | 1797428874878910464 |
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| author | Yuki Fujii Kazuyuki Matsumoto Hironari Kato Yosuke Saragai Saimon Takada Sho Mizukawa Shinichiro Muro Daisuke Uchida Takeshi Tomoda Shigeru Horiguchi Noriyuki Tanaka Hiroyuki Okada |
| author_facet | Yuki Fujii Kazuyuki Matsumoto Hironari Kato Yosuke Saragai Saimon Takada Sho Mizukawa Shinichiro Muro Daisuke Uchida Takeshi Tomoda Shigeru Horiguchi Noriyuki Tanaka Hiroyuki Okada |
| author_sort | Yuki Fujii |
| collection | DOAJ |
| description | Background/Aims This study aimed to examine the diagnostic ability of endoscopic ultrasonography (EUS) for major vascular invasion in pancreatic cancer and to evaluate the relationship between EUS findings and pathological distance. Methods In total, 57 consecutive patients who underwent EUS for pancreatic cancer before surgery were retrospectively reviewed. EUS image findings were divided into four types according to the relationship between the tumor and major vessel (types 1 and 2: invasion, types 3 and 4: non-invasion). We also compared the EUS findings and pathologically measured distances between the tumors and evaluated vessels. Results The sensitivity, specificity, and accuracy of EUS diagnosis for vascular invasion were 89%, 92%, and 91%, respectively, in the veins and 83%, 94%, and 93%, respectively, in the arteries. The pathologically evaluated distances of cases with type 2 EUS findings were significantly shorter than those of cases with type 3 EUS findings in both the major veins (median [interquartile range], 96 [0–742] µm vs. 2,833 [1,076–5,694] µm, p=0.012) and arteries (623 [0–854] µm vs. 3,097 [1,396–6,000] µm, p=0.0061). All cases with a distance of ≥1,000 µm between the tumors and main vessels were correctly diagnosed. Conclusions Tumors at a distance ≥1,000 µm from the main vessels were correctly diagnosed by EUS. |
| first_indexed | 2024-03-09T09:04:11Z |
| format | Article |
| id | doaj.art-7c11c5dac9cd4b958a041518eb3aeef3 |
| institution | Directory Open Access Journal |
| issn | 2234-2400 2234-2443 |
| language | English |
| last_indexed | 2024-03-09T09:04:11Z |
| publishDate | 2019-09-01 |
| publisher | Korean Society of Gastrointestinal Endoscopy |
| record_format | Article |
| series | Clinical Endoscopy |
| spelling | doaj.art-7c11c5dac9cd4b958a041518eb3aeef32023-12-02T10:42:19ZengKorean Society of Gastrointestinal EndoscopyClinical Endoscopy2234-24002234-24432019-09-0152547948510.5946/ce.2018.1637216Diagnostic Ability of Convex-Arrayed Endoscopic Ultrasonography for Major Vascular Invasion in Pancreatic CancerYuki Fujii0Kazuyuki Matsumoto1Hironari Kato2Yosuke Saragai3Saimon Takada4Sho Mizukawa5Shinichiro Muro6Daisuke Uchida7Takeshi Tomoda8Shigeru Horiguchi9Noriyuki Tanaka10Hiroyuki Okada11 Department of Gastroenterology and Hepatology, Dentistry and Pharmaceutical Science, Okayama, Japan Department of Gastroenterology and Hepatology, Dentistry and Pharmaceutical Science, Okayama, Japan Department of Gastroenterology and Hepatology, Dentistry and Pharmaceutical Science, Okayama, Japan Department of Gastroenterology and Hepatology, Dentistry and Pharmaceutical Science, Okayama, Japan Department of Gastroenterology and Hepatology, Dentistry and Pharmaceutical Science, Okayama, Japan Department of Gastroenterology and Hepatology, Dentistry and Pharmaceutical Science, Okayama, Japan Department of Gastroenterology and Hepatology, Dentistry and Pharmaceutical Science, Okayama, Japan Department of Gastroenterology and Hepatology, Dentistry and Pharmaceutical Science, Okayama, Japan Department of Gastroenterology and Hepatology, Dentistry and Pharmaceutical Science, Okayama, Japan Department of Gastroenterology and Hepatology, Dentistry and Pharmaceutical Science, Okayama, Japan Department of Pathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama, Japan Department of Gastroenterology and Hepatology, Dentistry and Pharmaceutical Science, Okayama, JapanBackground/Aims This study aimed to examine the diagnostic ability of endoscopic ultrasonography (EUS) for major vascular invasion in pancreatic cancer and to evaluate the relationship between EUS findings and pathological distance. Methods In total, 57 consecutive patients who underwent EUS for pancreatic cancer before surgery were retrospectively reviewed. EUS image findings were divided into four types according to the relationship between the tumor and major vessel (types 1 and 2: invasion, types 3 and 4: non-invasion). We also compared the EUS findings and pathologically measured distances between the tumors and evaluated vessels. Results The sensitivity, specificity, and accuracy of EUS diagnosis for vascular invasion were 89%, 92%, and 91%, respectively, in the veins and 83%, 94%, and 93%, respectively, in the arteries. The pathologically evaluated distances of cases with type 2 EUS findings were significantly shorter than those of cases with type 3 EUS findings in both the major veins (median [interquartile range], 96 [0–742] µm vs. 2,833 [1,076–5,694] µm, p=0.012) and arteries (623 [0–854] µm vs. 3,097 [1,396–6,000] µm, p=0.0061). All cases with a distance of ≥1,000 µm between the tumors and main vessels were correctly diagnosed. Conclusions Tumors at a distance ≥1,000 µm from the main vessels were correctly diagnosed by EUS.http://www.e-ce.org/upload/pdf/ce-2018-163.pdfEndoscopic ultrasonographyPancreatic cancerPathological distanceStagingVascular invasion |
| spellingShingle | Yuki Fujii Kazuyuki Matsumoto Hironari Kato Yosuke Saragai Saimon Takada Sho Mizukawa Shinichiro Muro Daisuke Uchida Takeshi Tomoda Shigeru Horiguchi Noriyuki Tanaka Hiroyuki Okada Diagnostic Ability of Convex-Arrayed Endoscopic Ultrasonography for Major Vascular Invasion in Pancreatic Cancer Clinical Endoscopy Endoscopic ultrasonography Pancreatic cancer Pathological distance Staging Vascular invasion |
| title | Diagnostic Ability of Convex-Arrayed Endoscopic Ultrasonography for Major Vascular Invasion in Pancreatic Cancer |
| title_full | Diagnostic Ability of Convex-Arrayed Endoscopic Ultrasonography for Major Vascular Invasion in Pancreatic Cancer |
| title_fullStr | Diagnostic Ability of Convex-Arrayed Endoscopic Ultrasonography for Major Vascular Invasion in Pancreatic Cancer |
| title_full_unstemmed | Diagnostic Ability of Convex-Arrayed Endoscopic Ultrasonography for Major Vascular Invasion in Pancreatic Cancer |
| title_short | Diagnostic Ability of Convex-Arrayed Endoscopic Ultrasonography for Major Vascular Invasion in Pancreatic Cancer |
| title_sort | diagnostic ability of convex arrayed endoscopic ultrasonography for major vascular invasion in pancreatic cancer |
| topic | Endoscopic ultrasonography Pancreatic cancer Pathological distance Staging Vascular invasion |
| url | http://www.e-ce.org/upload/pdf/ce-2018-163.pdf |
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