Transthyretin Amyloidosis Therapies: Guiding the Future

Transthyretin Amyloidosis Therapies: Guiding the Future

Transthyretin (TTR) amyloidosis (ATTR) is a progressive condition characterized by multiorgan accumulation of amyloid deposits composed of transthyretin (TTR) fibrils. Over the past decades, despite being a rare disease, ATTR amyloidosis has enabled top-tier therapeutics. In the 90s, organ transplan...

Full description

Bibliographic Details
Main Author:	Alejandra González-Duarte
Format:	Article
Language:	English
Published:	Permanyer 2021-01-01
Series:	Revista de Investigación Clínica
Subjects:	Transthyretin amyloidosis. Hereditary amyloidosis. siRNA. Lipid nanoparticles.
Online Access:	https://www.clinicalandtranslationalinvestigation.com/frame_esp.php?id=400

Similar Items

Hereditary systemic transthyretin amyloidosis: a clinical case and an opinion on the problem
by: A. S. Draganova, et al.
Published: (2019-07-01)

Hereditary cardiac amyloidosis associated with Pro24Ser transthyretin mutation: a case report
by: Hiroyuki Yamamoto, et al.
Published: (2018-12-01)

Inotersen Treatment for Patients with Hereditary Transthyretin Amyloidosis
by: Faruk Uğur Doğan, et al.
Published: (2019-03-01)

New simple and quick method to analyze serum variant transthyretins: direct MALDI method for the screening of hereditary transthyretin amyloidosis
by: Toshiya Nomura, et al.
Published: (2019-05-01)

Clinical characteristics in patients with hereditary amyloidosis with Glu54Gln transthyretin identified in the Romanian population
by: Andreea Jercan, et al.
Published: (2020-01-01)

Modified Technique of Ex-PRESS® Filtration Device Combined with a Scleral Pocket for Hereditary Transthyretin Amyloidosis (hATTR) Secondary Open-Angle Glaucoma
by: Vieira R, et al.
Published: (2023-01-01)

Clinical phenotypes and genetic features of hereditary transthyretin amyloidosis patients in China
by: Xinyue He, et al.
Published: (2022-09-01)

Leptomeningeal amyloidosis: features of the clinical picture (clinical observation)
by: E. I. Safiulina, et al.
Published: (2022-12-01)

Genomic Screening Identifies Individuals at High Risk for Hereditary Transthyretin Amyloidosis
by: Emily R. Soper, et al.
Published: (2021-01-01)

Specific Therapy for Transthyretin Cardiac Amyloidosis: A Systematic Literature Review and Evidence‐Based Recommendations
by: Nuno Marques, et al.
Published: (2020-10-01)

Diagnostic algorithm in transthyretin amyloidosis with cardiomyopathy
by: Mariana Gospodinova, et al.
Published: (2020-07-01)

The impact of inotersen on Neuropathy Impairment Score in patients with hereditary transthyretin amyloidosis with polyneuropathy
by: Aaron Yarlas, et al.
Published: (2023-03-01)

Early-Onset of Transthyretin Amyloidosis in a Young Afro-Caribbean Woman With Thr60Ala Mutation
by: Stormy C. Keppel, MD, et al.
Published: (2020-11-01)

Hereditary transthyretin-related amyloidosis is frequent in polyneuropathy and cardiomyopathy of no obvious aetiology
by: Volha Skrahina, et al.
Published: (2021-01-01)

Disease-Modifying Therapy for Transthyretin Amyloidosis
by: Nowell M. Fine, MD, SM
Published: (2020-11-01)

Extracellular Vesicles Contribute to the Metabolism of Transthyretin Amyloid in Hereditary Transthyretin Amyloidosis
by: Hiroki Yamaguchi, et al.
Published: (2022-03-01)

Late-Onset Hereditary Transthyretin Amyloidosis Val30Met in an Elderly Person in a Non-Endemic Area
by: Wang S, et al.
Published: (2022-06-01)

Plasma growth differentiation factor 15: a novel tool to detect early changes of hereditary transthyretin amyloidosis
by: Masamitsu Okada, et al.
Published: (2021-04-01)

Italian Real-Life Experience of Patients with Hereditary Transthyretin Amyloidosis Treated with Patisiran
by: Di Stefano V, et al.
Published: (2022-05-01)

Vitreous amyloidosis with autonomic neuropathy of the digestive tract associated with a novel transthyretin p.Gly87Arg variant in a Bangladeshi patient: a case report
by: Benjamin Terrier, et al.
Published: (2017-08-01)

A Brief Journey through Protein Misfolding in Transthyretin Amyloidosis (ATTR Amyloidosis)
by: Alejandra Gonzalez-Duarte, et al.
Published: (2021-12-01)

An unusual case of hereditary transthyretin‐related amyloidosis and ulcerative colitis in a young Indian girl
by: Vishal Sharma, et al.
Published: (2020-04-01)

Updated Evaluation of the Safety, Efficacy and Tolerability of Tafamidis in the Treatment of Hereditary Transthyretin Amyloid Polyneuropathy
by: Falcão de Campos C, et al.
Published: (2023-02-01)

Diagnosis and Screening of Patients with Hereditary Transthyretin Amyloidosis (hATTR): Current Strategies and Guidelines
by: Benson MD, et al.
Published: (2020-08-01)

Clinical characteristics and prognosis of Chinese patients with hereditary transthyretin amyloid cardiomyopathy
by: Shan He, et al.
Published: (2019-11-01)

EGCG-Mediated Protection of Transthyretin Amyloidosis by Stabilizing Transthyretin Tetramers and Disrupting Transthyretin Aggregates
by: Huizhen Zou, et al.
Published: (2023-09-01)

Targeted sequencing of selected functional genes in patients with wild-type transthyretin amyloidosis
by: Inmaculada Moreno-Gázquez, et al.
Published: (2023-10-01)

Case Report: Hereditary transthyretin (ATTRv) amyloidosis: The p.G103R mutation of the transthyretin gene in a Han Chinese family is associated with vitreous hemorrhage
by: Junhui Shen, et al.
Published: (2022-09-01)

Clinical Profile and Prognosis of Hereditary Transthyretin Amyloid Cardiomyopathy: A Single-Center Study in South China
by: Shuai Wang, et al.
Published: (2022-06-01)

Recommendations for pre-symptomatic genetic testing for hereditary transthyretin amyloidosis in the era of effective therapy: a multicenter Italian consensus
by: M. Grandis, et al.
Published: (2020-12-01)

Urinary Transthyretin as a Biomarker in ATTRv Val50Met Amyloidosis
by: Hiroaki Matsushita, et al.
Published: (2022-06-01)

Lack of Association Between Neurohormonal Blockade and Survival in Transthyretin Cardiac Amyloidosis
by: Richard K. Cheng, et al.
Published: (2021-12-01)

Monitoring the Patient with Retinal Angiopathy Associated with Hereditary Transthyretin Amyloidosis: Current Perspectives
by: Marques JH, et al.
Published: (2022-07-01)

The Transthyretin/Oleuropein Aglycone Complex: A New Tool against TTR Amyloidosis
by: Francesco Bemporad, et al.
Published: (2022-02-01)

Transthyretin cardiac amyloidosis in aortic stenosis: Prevalence, diagnostic challenges, and clinical implications
by: Giedre Balciunaite, et al.
Published: (2020-03-01)

Transthyretin cardiac amyloidosis: an under-diagnosed cause of heart failure
by: Gabriela Molina O, et al.
Published: (2014-11-01)

Oral Therapy for the Treatment of Transthyretin-Related Amyloid Cardiomyopathy
by: Mario Nuvolone, et al.
Published: (2022-12-01)

A 15-year consolidated overview of data in over 6000 patients from the Transthyretin Amyloidosis Outcomes Survey (THAOS)
by: Luca Gentile, et al.
Published: (2023-11-01)

Modulation of the Mechanisms Driving Transthyretin Amyloidosis
by: Filipa Bezerra, et al.
Published: (2020-12-01)

Clinical and Genotype Characteristics and Symptom Migration in Patients With Mixed Phenotype Transthyretin Amyloidosis from the Transthyretin Amyloidosis Outcomes Survey
by: Juan González-Moreno, et al.
Published: (2023-12-01)