A randomized crossover study to evaluate local tolerability following subcutaneous administration of a new depot medroxyprogesterone acetate contraceptive formulation

A randomized crossover study to evaluate local tolerability following subcutaneous administration of a new depot medroxyprogesterone acetate contraceptive formulation

Objectives: This study aimed to evaluate and compare local tolerability of investigational drug TV-46046 and reference drug Depo-subQ Provera 104, both containing medroxyprogesterone acetate (MPA) as an active ingredient. Study design: We conducted a randomized, crossover, single-center study. Twent...

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Bibliographic Details
Main Authors: Vera Halpern, Angie Wheeless, Vivian Brache, Anja Lendvay, Leila Cochón, Douglas Taylor, Laneta J. Dorflinger
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Contraception: X
Subjects:
Contraception
Depot medroxyprogesterone acetate
Hypopigmentation
Local tolerability
Safety
Skin discoloration
Online Access:http://www.sciencedirect.com/science/article/pii/S2590151623000126

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