Engineering of a functional γ-tocopherol transfer protein

Engineering of a functional γ-tocopherol transfer protein

α-tocopherol transfer protein (TTP) was previously reported to self-aggregate into 24-meric spheres (α-TTPS) and to possess transcytotic potency across mono-layers of human umbilical vein endothelial cells (HUVECs). In this work, we describe the characterisation of a functional TTP variant with its...

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Bibliographic Details
Main Authors: Walter Aeschimann, Stephan Kammer, Stefanie Staats, Petra Schneider, Gisbert Schneider, Gerald Rimbach, Michele Cascella, Achim Stocker
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Redox Biology
Subjects:
Nanoparticle
Vitamin E
Antioxidant
Transcytosis
Cytokine
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231720309782

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