Mortality in hospitalized older adults associated with Clostridium difficile infection at a district hospital
Clostridium difficile is the most common cause of hospital acquired infectious diarrhea in the developed world and has re-emerged in recent years with apparent greater morbidity and mortality. Despite this, there is little recent published data from the UK concerning associated mortality. We perform...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2010-06-01
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| Series: | Infectious Disease Reports |
| Subjects: | |
| Online Access: | http://www.pagepress.org/journals/index.php/idr/article/view/1824 |
| _version_ | 1818865118713217024 |
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| author | Johannis Andreas Karas Simon Bradshaw Wabas Mahmud David A. Enoch |
| author_facet | Johannis Andreas Karas Simon Bradshaw Wabas Mahmud David A. Enoch |
| author_sort | Johannis Andreas Karas |
| collection | DOAJ |
| description | Clostridium difficile is the most common cause of hospital acquired infectious diarrhea in the developed world and has re-emerged in recent years with apparent greater morbidity and mortality. Despite this, there is little recent published data from the UK concerning associated mortality. We performed a case control study at a UK district general hospital of 66 hospitalized patients over the age of 65 years with C. difficile infection compared to 3-5 controls matched for age, sex and minimum length of stay. We found a significant excess mortality of 11.5% at seven days, 26.2% at 30 days, 38.1% at 90 days and 41.4% at 180 days. C. difficile infection in hospitalized elderly patients may contribute to long-term mortality or be a marker of poor prognosis and cases may require more intensive long-term follow up to improve mortality. |
| first_indexed | 2024-12-19T10:42:28Z |
| format | Article |
| id | doaj.art-7c2344fec7ea47c784c480509f16da59 |
| institution | Directory Open Access Journal |
| issn | 2036-7430 2036-7449 |
| language | English |
| last_indexed | 2024-12-19T10:42:28Z |
| publishDate | 2010-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Infectious Disease Reports |
| spelling | doaj.art-7c2344fec7ea47c784c480509f16da592022-12-21T20:25:24ZengMDPI AGInfectious Disease Reports2036-74302036-74492010-06-0121e8e810.4081/idr.2010.18241195Mortality in hospitalized older adults associated with Clostridium difficile infection at a district hospitalJohannis Andreas Karas0Simon Bradshaw1Wabas Mahmud2David A. Enoch3Health Protection AgencyHinchingbrooke HospitalHinchingbrooke HospitalHealth Protection AgencyClostridium difficile is the most common cause of hospital acquired infectious diarrhea in the developed world and has re-emerged in recent years with apparent greater morbidity and mortality. Despite this, there is little recent published data from the UK concerning associated mortality. We performed a case control study at a UK district general hospital of 66 hospitalized patients over the age of 65 years with C. difficile infection compared to 3-5 controls matched for age, sex and minimum length of stay. We found a significant excess mortality of 11.5% at seven days, 26.2% at 30 days, 38.1% at 90 days and 41.4% at 180 days. C. difficile infection in hospitalized elderly patients may contribute to long-term mortality or be a marker of poor prognosis and cases may require more intensive long-term follow up to improve mortality.http://www.pagepress.org/journals/index.php/idr/article/view/1824Clostridium difficilemortality |
| spellingShingle | Johannis Andreas Karas Simon Bradshaw Wabas Mahmud David A. Enoch Mortality in hospitalized older adults associated with Clostridium difficile infection at a district hospital Infectious Disease Reports Clostridium difficile mortality |
| title | Mortality in hospitalized older adults associated with Clostridium difficile infection at a district hospital |
| title_full | Mortality in hospitalized older adults associated with Clostridium difficile infection at a district hospital |
| title_fullStr | Mortality in hospitalized older adults associated with Clostridium difficile infection at a district hospital |
| title_full_unstemmed | Mortality in hospitalized older adults associated with Clostridium difficile infection at a district hospital |
| title_short | Mortality in hospitalized older adults associated with Clostridium difficile infection at a district hospital |
| title_sort | mortality in hospitalized older adults associated with clostridium difficile infection at a district hospital |
| topic | Clostridium difficile mortality |
| url | http://www.pagepress.org/journals/index.php/idr/article/view/1824 |
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