Canine induced pluripotent stem cells efficiently differentiate into definitive endoderm in 3D cell culture conditions using high-dose activin A
Introduction: Endoderm-derived organs support indispensable functions in the body. Pluripotent stem cells can generate endoderm-derived cells or tissues and have excellent therapeutic potential to replace the functions of endodermal tissues. However, there is no viable method to induce endodermal pr...
Main Authors: | Masaya Tsukamoto, Kazuto Kimura, Takumi Yoshida, Kikuya Sugiura, Shingo Hatoya |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-12-01
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Series: | Regenerative Therapy |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352320422000992 |
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