Mendelian randomization analysis of 37 clinical factors and coronary artery disease in East Asian and European populations

Mendelian randomization analysis of 37 clinical factors and coronary artery disease in East Asian and European populations

Abstract Background Coronary artery disease (CAD) remains the leading cause of mortality worldwide despite enormous efforts devoted to its prevention and treatment. While many genetic loci have been identified to associate with CAD, the intermediate causal risk factors and etiology have not been ful...

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Bibliographic Details
Main Authors: Kai Wang, Xian Shi, Ziwei Zhu, Xingjie Hao, Liangkai Chen, Shanshan Cheng, Roger S. Y. Foo, Chaolong Wang
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Genome Medicine
Subjects:
Mendelian randomization
Clinical factors
Coronary artery disease
Causal inference
Red blood cells
Uric acid
Online Access:https://doi.org/10.1186/s13073-022-01067-1

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