c-Abl Tyrosine Kinase Is Required for BDNF-Induced Dendritic Branching and Growth

c-Abl Tyrosine Kinase Is Required for BDNF-Induced Dendritic Branching and Growth

Brain-derived neurotrophic factor (BDNF) induces activation of the TrkB receptor and several downstream pathways (MAPK, PI3K, PLC-γ), leading to neuronal survival, growth, and plasticity. It has been well established that TrkB signaling regulation is required for neurite formation and dendritic arbo...

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Bibliographic Details
Main Authors: América Chandía-Cristi, Nicolás Stuardo, Cristian Trejos, Nancy Leal, Daniela Urrutia, Francisca C. Bronfman, Alejandra Álvarez Rojas
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
dendritic arborization
c-Abl
BDNF/TrkB pathway
Online Access:https://www.mdpi.com/1422-0067/24/3/1944

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