The Antidepressant Mirtazapine Rapidly Shifts Hepatic B Cell Populations and Functional Cytokine Signatures in the Mouse

The Antidepressant Mirtazapine Rapidly Shifts Hepatic B Cell Populations and Functional Cytokine Signatures in the Mouse

IntroductionB cells are important regulators of both adaptive and innate immunity. The normal liver contains significant numbers of B cells, and their numbers increase dramatically in immune-mediated liver diseases. Our previous observations suggest a hepatoprotective effect of the antidepressant mi...

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Bibliographic Details
Main Authors: Wagdi Almishri, Rachelle P. Davis, Abdel-Aziz Shaheen, Mohammed O. Altonsy, Craig N. Jenne, Mark G. Swain
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
liver disease
immunity
B cells
inflammation
intravital microscopy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.622537/full

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