Factors Contributing to Surgical Site Infections: A Comprehensive Systematic Review of Etiology and Risk Factors

Surgical site infections persist as a substantial concern within the realm of hospital-acquired infections. This enduring issue is further compounded by the mounting challenge of antibiotic resistance, a surge in surgical interventions, and the presence of comorbidities among patients. Thus, a compr...

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Main Authors: Alexandra Bucataru, Maria Balasoiu, Alice Elena Ghenea, Ovidiu Mircea Zlatian, Dan Dumitru Vulcanescu, Florin George Horhat, Iulia Cristina Bagiu, Virgiliu Bogdan Sorop, Madalina Ioana Sorop, Andrada Oprisoni, Estera Boeriu, Stelian Stefanita Mogoanta
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Clinics and Practice
Subjects:
Online Access:https://www.mdpi.com/2039-7283/14/1/6
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author Alexandra Bucataru
Maria Balasoiu
Alice Elena Ghenea
Ovidiu Mircea Zlatian
Dan Dumitru Vulcanescu
Florin George Horhat
Iulia Cristina Bagiu
Virgiliu Bogdan Sorop
Madalina Ioana Sorop
Andrada Oprisoni
Estera Boeriu
Stelian Stefanita Mogoanta
author_facet Alexandra Bucataru
Maria Balasoiu
Alice Elena Ghenea
Ovidiu Mircea Zlatian
Dan Dumitru Vulcanescu
Florin George Horhat
Iulia Cristina Bagiu
Virgiliu Bogdan Sorop
Madalina Ioana Sorop
Andrada Oprisoni
Estera Boeriu
Stelian Stefanita Mogoanta
author_sort Alexandra Bucataru
collection DOAJ
description Surgical site infections persist as a substantial concern within the realm of hospital-acquired infections. This enduring issue is further compounded by the mounting challenge of antibiotic resistance, a surge in surgical interventions, and the presence of comorbidities among patients. Thus, a comprehensive exploration of all discernible risk factors, as well as proactive preventive and prophylactic strategies, becomes imperative. Moreover, the prevalence of multidrug-resistant microorganisms has reached alarming proportions. Consequently, there is an acute need to investigate and scrutinize all potential therapeutic interventions to counter this burgeoning threat. Consequently, the primary objective of this review is to meticulously assess the origins and risk elements intertwined with surgical site infections across a diverse spectrum of surgical procedures. As the medical landscape continues to evolve, this critical analysis seeks to provide a nuanced understanding of the multi-faceted factors contributing to surgical site infections, with the overarching aim of facilitating more effective management and mitigation strategies. By exploring these dimensions comprehensively, we endeavor to enhance patient safety and the quality of surgical care in this era of evolving healthcare challenges.
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spelling doaj.art-7c2efa6bd4604d49aa6bffc182708f372024-02-23T15:12:44ZengMDPI AGClinics and Practice2039-72832023-12-01141526810.3390/clinpract14010006Factors Contributing to Surgical Site Infections: A Comprehensive Systematic Review of Etiology and Risk FactorsAlexandra Bucataru0Maria Balasoiu1Alice Elena Ghenea2Ovidiu Mircea Zlatian3Dan Dumitru Vulcanescu4Florin George Horhat5Iulia Cristina Bagiu6Virgiliu Bogdan Sorop7Madalina Ioana Sorop8Andrada Oprisoni9Estera Boeriu10Stelian Stefanita Mogoanta11Doctoral School Department, University of Medicine and Pharmacy of Craiova, 200349 Craiova, RomaniaDepartment of Bacteriology-Virology-Parasitology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, RomaniaDepartment of Bacteriology-Virology-Parasitology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, RomaniaDepartment of Bacteriology-Virology-Parasitology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, RomaniaDepartment of Microbiology, “Victor Babes” University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, RomaniaDepartment of Microbiology, “Victor Babes” University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, RomaniaDepartment of Microbiology, “Victor Babes” University of Medicine and Pharmacy, Eftimie Murgu Square 2, 300041 Timisoara, RomaniaDepartment of Obstetrics and Gynecology, “Victor Babes” University of Medicine and Pharmacy, Eftimie Murgu Square, No. 2, 300041 Timisoara, RomaniaDoctoral School, “Victor Babes” University of Medicine and Pharmacy, 300041 Timisoara, RomaniaDepartment of Pediatrics, Discipline of Pediatric Oncology and Hematology, “Victor Babes” University of Medicine and Pharmacy, Eftimie Murgu Square, No. 2, 300041 Timisoara, RomaniaDepartment of Pediatrics, Discipline of Pediatric Oncology and Hematology, “Victor Babes” University of Medicine and Pharmacy, Eftimie Murgu Square, No. 2, 300041 Timisoara, RomaniaThird General Surgery Department, Clinical Emergency County Hospital, 200642 Craiova, RomaniaSurgical site infections persist as a substantial concern within the realm of hospital-acquired infections. This enduring issue is further compounded by the mounting challenge of antibiotic resistance, a surge in surgical interventions, and the presence of comorbidities among patients. Thus, a comprehensive exploration of all discernible risk factors, as well as proactive preventive and prophylactic strategies, becomes imperative. Moreover, the prevalence of multidrug-resistant microorganisms has reached alarming proportions. Consequently, there is an acute need to investigate and scrutinize all potential therapeutic interventions to counter this burgeoning threat. Consequently, the primary objective of this review is to meticulously assess the origins and risk elements intertwined with surgical site infections across a diverse spectrum of surgical procedures. As the medical landscape continues to evolve, this critical analysis seeks to provide a nuanced understanding of the multi-faceted factors contributing to surgical site infections, with the overarching aim of facilitating more effective management and mitigation strategies. By exploring these dimensions comprehensively, we endeavor to enhance patient safety and the quality of surgical care in this era of evolving healthcare challenges.https://www.mdpi.com/2039-7283/14/1/6surgical site infections (SSIs)antimicrobial resistancerisk factors
spellingShingle Alexandra Bucataru
Maria Balasoiu
Alice Elena Ghenea
Ovidiu Mircea Zlatian
Dan Dumitru Vulcanescu
Florin George Horhat
Iulia Cristina Bagiu
Virgiliu Bogdan Sorop
Madalina Ioana Sorop
Andrada Oprisoni
Estera Boeriu
Stelian Stefanita Mogoanta
Factors Contributing to Surgical Site Infections: A Comprehensive Systematic Review of Etiology and Risk Factors
Clinics and Practice
surgical site infections (SSIs)
antimicrobial resistance
risk factors
title Factors Contributing to Surgical Site Infections: A Comprehensive Systematic Review of Etiology and Risk Factors
title_full Factors Contributing to Surgical Site Infections: A Comprehensive Systematic Review of Etiology and Risk Factors
title_fullStr Factors Contributing to Surgical Site Infections: A Comprehensive Systematic Review of Etiology and Risk Factors
title_full_unstemmed Factors Contributing to Surgical Site Infections: A Comprehensive Systematic Review of Etiology and Risk Factors
title_short Factors Contributing to Surgical Site Infections: A Comprehensive Systematic Review of Etiology and Risk Factors
title_sort factors contributing to surgical site infections a comprehensive systematic review of etiology and risk factors
topic surgical site infections (SSIs)
antimicrobial resistance
risk factors
url https://www.mdpi.com/2039-7283/14/1/6
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