Proper surgical extent for clinical Stage I right colon cancer
Purpose: Pre-operative evaluation identifying clinical-stage affects the decision regarding the extent of surgical resection in right colon cancer. This study was designed to predict a proper surgical resection through the prognosis of clinical Stage I right colon cancer. Patients and Methods: We in...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | Journal of Minimal Access Surgery |
| Subjects: | |
| Online Access: | http://www.journalofmas.com/article.asp?issn=0972-9941;year=2022;volume=18;issue=2;spage=224;epage=229;aulast=Kwak |
| _version_ | 1798021725524328448 |
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| author | Han Deok Kwak Jun Seong Chung Jae Kyun Ju Soo Young Lee Chang Hyun Kim Hyeong Rok Kim |
| author_facet | Han Deok Kwak Jun Seong Chung Jae Kyun Ju Soo Young Lee Chang Hyun Kim Hyeong Rok Kim |
| author_sort | Han Deok Kwak |
| collection | DOAJ |
| description | Purpose: Pre-operative evaluation identifying clinical-stage affects the decision regarding the extent of surgical resection in right colon cancer. This study was designed to predict a proper surgical resection through the prognosis of clinical Stage I right colon cancer.
Patients and Methods: We included patients who were diagnosed with clinical and pathological Stage I right-sided colon cancer, including appendiceal, caecal, ascending, hepatic flexure and proximal transverse colon cancer, between August 2010 and December 2016 in two tertiary teaching hospitals. Patients who underwent open surgeries were excluded because laparoscopic surgery is the initial approach for colorectal cancer in our institutions.
Results: Eighty patients with clinical Stage I and 104 patients with pathological Stage I were included in the study. The biopsy reports showed that the tumour size was larger in the clinical Stage I group than in the pathological Stage I group (3.4 vs. 2.3 cm, P < 0.001). Further, the clinical Stage I group had some pathological Stage III cases (positive lymph nodes, P = 0.023). The clinical Stage I group had a higher rate of distant metastases (P = 0.046) and a lower rate of overall (P = 0.031) and cancer-specific survival (P = 0.021) than the pathological Stage I group. Compared to pathological Stage II included in the period, some of the survival curves were located below the pathological Stage II, but there was no statistical difference.
Conclusion: The study results show that even clinical Stage I cases, radical resection should be considered in accordance with T3 and T4 tumours. |
| first_indexed | 2024-04-11T17:18:10Z |
| format | Article |
| id | doaj.art-7c2f4d44b20644d4a99eea01eade3722 |
| institution | Directory Open Access Journal |
| issn | 0972-9941 1998-3921 |
| language | English |
| last_indexed | 2024-04-11T17:18:10Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Minimal Access Surgery |
| spelling | doaj.art-7c2f4d44b20644d4a99eea01eade37222022-12-22T04:12:35ZengWolters Kluwer Medknow PublicationsJournal of Minimal Access Surgery0972-99411998-39212022-01-0118222422910.4103/jmas.JMAS_9_21Proper surgical extent for clinical Stage I right colon cancerHan Deok KwakJun Seong ChungJae Kyun JuSoo Young LeeChang Hyun KimHyeong Rok KimPurpose: Pre-operative evaluation identifying clinical-stage affects the decision regarding the extent of surgical resection in right colon cancer. This study was designed to predict a proper surgical resection through the prognosis of clinical Stage I right colon cancer. Patients and Methods: We included patients who were diagnosed with clinical and pathological Stage I right-sided colon cancer, including appendiceal, caecal, ascending, hepatic flexure and proximal transverse colon cancer, between August 2010 and December 2016 in two tertiary teaching hospitals. Patients who underwent open surgeries were excluded because laparoscopic surgery is the initial approach for colorectal cancer in our institutions. Results: Eighty patients with clinical Stage I and 104 patients with pathological Stage I were included in the study. The biopsy reports showed that the tumour size was larger in the clinical Stage I group than in the pathological Stage I group (3.4 vs. 2.3 cm, P < 0.001). Further, the clinical Stage I group had some pathological Stage III cases (positive lymph nodes, P = 0.023). The clinical Stage I group had a higher rate of distant metastases (P = 0.046) and a lower rate of overall (P = 0.031) and cancer-specific survival (P = 0.021) than the pathological Stage I group. Compared to pathological Stage II included in the period, some of the survival curves were located below the pathological Stage II, but there was no statistical difference. Conclusion: The study results show that even clinical Stage I cases, radical resection should be considered in accordance with T3 and T4 tumours.http://www.journalofmas.com/article.asp?issn=0972-9941;year=2022;volume=18;issue=2;spage=224;epage=229;aulast=Kwakclinical stageoutcomepathological stageright colon cancerstage i |
| spellingShingle | Han Deok Kwak Jun Seong Chung Jae Kyun Ju Soo Young Lee Chang Hyun Kim Hyeong Rok Kim Proper surgical extent for clinical Stage I right colon cancer Journal of Minimal Access Surgery clinical stage outcome pathological stage right colon cancer stage i |
| title | Proper surgical extent for clinical Stage I right colon cancer |
| title_full | Proper surgical extent for clinical Stage I right colon cancer |
| title_fullStr | Proper surgical extent for clinical Stage I right colon cancer |
| title_full_unstemmed | Proper surgical extent for clinical Stage I right colon cancer |
| title_short | Proper surgical extent for clinical Stage I right colon cancer |
| title_sort | proper surgical extent for clinical stage i right colon cancer |
| topic | clinical stage outcome pathological stage right colon cancer stage i |
| url | http://www.journalofmas.com/article.asp?issn=0972-9941;year=2022;volume=18;issue=2;spage=224;epage=229;aulast=Kwak |
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