Multiscale modelling of vascular tumour growth in 3D: the roles of domain size and boundary conditions.

Multiscale modelling of vascular tumour growth in 3D: the roles of domain size and boundary conditions.

We investigate a three-dimensional multiscale model of vascular tumour growth, which couples blood flow, angiogenesis, vascular remodelling, nutrient/growth factor transport, movement of, and interactions between, normal and tumour cells, and nutrient-dependent cell cycle dynamics within each cell....

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Bibliographic Details
Main Authors:	Holger Perfahl, Helen M Byrne, Tingan Chen, Veronica Estrella, Tomás Alarcón, Alexei Lapin, Robert A Gatenby, Robert J Gillies, Mark C Lloyd, Philip K Maini, Matthias Reuss, Markus R Owen
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2011-04-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3076378?pdf=render

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