Effect of long work hours and shift work on high-sensitivity C-reactive protein levels among Korean workers
OBJECTIVE: We aimed to investigate the association between low-grade inflammation as indicated by high-sensitivity C-reactive protein (hsCRP) level and organizational factors, such as work hours and shift work. METHODS: We evaluated 7470 young and middle-aged workers who participated in the Korea Na...
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| Format: | Article |
| Language: | English |
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Nordic Association of Occupational Safety and Health (NOROSH)
2021-04-01
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| Series: | Scandinavian Journal of Work, Environment & Health |
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| Online Access: |
https://www.sjweh.fi/show_abstract.php?abstract_id=3933
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| _version_ | 1818921559272718336 |
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| author | Wanhyung Lee Seong-Kyu Kang Won-Jun Choi |
| author_facet | Wanhyung Lee Seong-Kyu Kang Won-Jun Choi |
| author_sort | Wanhyung Lee |
| collection | DOAJ |
| description | OBJECTIVE: We aimed to investigate the association between low-grade inflammation as indicated by high-sensitivity C-reactive protein (hsCRP) level and organizational factors, such as work hours and shift work. METHODS: We evaluated 7470 young and middle-aged workers who participated in the Korea National Health and Nutrition Examination Surveys from 2015–2018. Work hours were determined from self-reported questionnaires. Shift work was defined as a non-daytime fixed work schedule. An interaction effect between shift work and long work hours on the hsCRP level was estimated using relative excess risk due to interaction (RERI) and attributable proportion (AP) with 95% confidence intervals (CI). RESULTS: Increased hsCRP levels were prevalent in 25.2% of the study population. There was a significant association between long work hours and increased hsCRP, especially among middle-aged men [odds ratio (OR) 1.50 (95% CI 1.20–1.87) for moderately increased hsCRP and OR 1.62 (95% CI 1.14–2.30) for highly increased hsCRP]. There was a significant interaction effect between long work hours and shift work on increased hsCRP among middle-aged workers. The RERI were 0.03 (95% CI 0.02–0.04) and 0.56 (95% CI 0.45–0.68) among middle-aged men and women, respectively. The AP were 0.02 (95% CI 0.01–0.03) and 0.36 (95% CI 0.31–0.40) among middle-aged men and women, respectively. CONCLUSION: There was no significant association between shift work and the level of hsCRP. Long work hours were related to low-grade inflammatory processes, but only in middle-aged workers. There was an interaction effect between long work hours and shift work for increased hsCRP, especially in middle-aged women. |
| first_indexed | 2024-12-20T01:39:34Z |
| format | Article |
| id | doaj.art-7c3b0bb4eddc4d479f85426b561a9a86 |
| institution | Directory Open Access Journal |
| issn | 0355-3140 1795-990X |
| language | English |
| last_indexed | 2024-12-20T01:39:34Z |
| publishDate | 2021-04-01 |
| publisher | Nordic Association of Occupational Safety and Health (NOROSH) |
| record_format | Article |
| series | Scandinavian Journal of Work, Environment & Health |
| spelling | doaj.art-7c3b0bb4eddc4d479f85426b561a9a862022-12-21T19:57:56ZengNordic Association of Occupational Safety and Health (NOROSH)Scandinavian Journal of Work, Environment & Health0355-31401795-990X2021-04-0147320020710.5271/sjweh.39333933Effect of long work hours and shift work on high-sensitivity C-reactive protein levels among Korean workersWanhyung LeeSeong-Kyu KangWon-Jun Choi0Department of Occupational and Environmental Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Republic of Korea.OBJECTIVE: We aimed to investigate the association between low-grade inflammation as indicated by high-sensitivity C-reactive protein (hsCRP) level and organizational factors, such as work hours and shift work. METHODS: We evaluated 7470 young and middle-aged workers who participated in the Korea National Health and Nutrition Examination Surveys from 2015–2018. Work hours were determined from self-reported questionnaires. Shift work was defined as a non-daytime fixed work schedule. An interaction effect between shift work and long work hours on the hsCRP level was estimated using relative excess risk due to interaction (RERI) and attributable proportion (AP) with 95% confidence intervals (CI). RESULTS: Increased hsCRP levels were prevalent in 25.2% of the study population. There was a significant association between long work hours and increased hsCRP, especially among middle-aged men [odds ratio (OR) 1.50 (95% CI 1.20–1.87) for moderately increased hsCRP and OR 1.62 (95% CI 1.14–2.30) for highly increased hsCRP]. There was a significant interaction effect between long work hours and shift work on increased hsCRP among middle-aged workers. The RERI were 0.03 (95% CI 0.02–0.04) and 0.56 (95% CI 0.45–0.68) among middle-aged men and women, respectively. The AP were 0.02 (95% CI 0.01–0.03) and 0.36 (95% CI 0.31–0.40) among middle-aged men and women, respectively. CONCLUSION: There was no significant association between shift work and the level of hsCRP. Long work hours were related to low-grade inflammatory processes, but only in middle-aged workers. There was an interaction effect between long work hours and shift work for increased hsCRP, especially in middle-aged women. https://www.sjweh.fi/show_abstract.php?abstract_id=3933 long work hourknhaneshscrpkorean workercardiovascular diseaseinflammationshift workerc-reactive proteinkoreaworking hourwork hour |
| spellingShingle | Wanhyung Lee Seong-Kyu Kang Won-Jun Choi Effect of long work hours and shift work on high-sensitivity C-reactive protein levels among Korean workers Scandinavian Journal of Work, Environment & Health long work hour knhanes hscrp korean worker cardiovascular disease inflammation shift worker c-reactive protein korea working hour work hour |
| title | Effect of long work hours and shift work on high-sensitivity C-reactive protein levels among Korean workers |
| title_full | Effect of long work hours and shift work on high-sensitivity C-reactive protein levels among Korean workers |
| title_fullStr | Effect of long work hours and shift work on high-sensitivity C-reactive protein levels among Korean workers |
| title_full_unstemmed | Effect of long work hours and shift work on high-sensitivity C-reactive protein levels among Korean workers |
| title_short | Effect of long work hours and shift work on high-sensitivity C-reactive protein levels among Korean workers |
| title_sort | effect of long work hours and shift work on high sensitivity c reactive protein levels among korean workers |
| topic | long work hour knhanes hscrp korean worker cardiovascular disease inflammation shift worker c-reactive protein korea working hour work hour |
| url |
https://www.sjweh.fi/show_abstract.php?abstract_id=3933
|
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