Citromycin Isolated from the Antarctic Marine-Derived Fungi, <i>Sporothrix</i> sp., Inhibits Ovarian Cancer Cell Invasion via Suppression of ERK Signaling

Citromycin Isolated from the Antarctic Marine-Derived Fungi, <i>Sporothrix</i> sp., Inhibits Ovarian Cancer Cell Invasion via Suppression of ERK Signaling

Recently, microorganisms and their metabolites in the Antarctic marine environment have attracted attention as useful sources for novel therapeutics, including anticancer drugs. Here, we investigated the effects of citromycin, isolated from the Antarctic marine-derived fungus, <i>Sporothrix<...

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Bibliographic Details
Main Authors: He Yun Choi, Ji-Hye Ahn, Haeun Kwon, Joung Han Yim, Dongho Lee, Jung-Hye Choi
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Marine Drugs
Subjects:
citromycin
<i>Sporothrix</i> sp.
ovarian cancer
invasion
MMP2 and MMP9
ERK1/2 pathway
Online Access:https://www.mdpi.com/1660-3397/20/5/275

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