A young man with polyuria and lethargy

We report a 20-year-old man who presented to our emergency room with a history of polyuria, weakness, constipation, nausea, and vomiting of two months duration. History and clinical examination revealed a significant weight loss and mild hepatomegaly. Laboratory investigations revealed hypokalemia,...

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Main Authors: Salman Imtiaz, Shahid Qayyum, Hala Kafouri, Habib ur Rehman, Mohammad Al Khoiter, Akram Askar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2011-01-01
Series:Saudi Journal of Kidney Diseases and Transplantation
Online Access:http://www.sjkdt.org/article.asp?issn=1319-2442;year=2011;volume=22;issue=4;spage=847;epage=852;aulast=Imtiaz
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author Salman Imtiaz
Shahid Qayyum
Hala Kafouri
Habib ur Rehman
Mohammad Al Khoiter
Akram Askar
author_facet Salman Imtiaz
Shahid Qayyum
Hala Kafouri
Habib ur Rehman
Mohammad Al Khoiter
Akram Askar
author_sort Salman Imtiaz
collection DOAJ
description We report a 20-year-old man who presented to our emergency room with a history of polyuria, weakness, constipation, nausea, and vomiting of two months duration. History and clinical examination revealed a significant weight loss and mild hepatomegaly. Laboratory investigations revealed hypokalemia, hypernatremia, and severe metabolic acidosis and anemia. Ultra-sound of the abdomen revealed enlarged kidneys without hydronerphrosis. The patient developed paralysis due to further decline in serum potassium level, which improved after an aggressive fluid and electrolyte management. He was investigated extensively for polyuria and type of acidosis. The kidney biopsy showed interstitial leukemic infiltration. He was managed accordingly and recovered from the condition. This case demonstrates an unusual presentation of a hematological malignancy, which was a diagnostic as well as a management challenge.
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spelling doaj.art-7c3f1fbca6e04256822caeca6475b6672022-12-22T03:39:28ZengWolters Kluwer Medknow PublicationsSaudi Journal of Kidney Diseases and Transplantation1319-24422011-01-01224847852A young man with polyuria and lethargySalman ImtiazShahid QayyumHala KafouriHabib ur RehmanMohammad Al KhoiterAkram AskarWe report a 20-year-old man who presented to our emergency room with a history of polyuria, weakness, constipation, nausea, and vomiting of two months duration. History and clinical examination revealed a significant weight loss and mild hepatomegaly. Laboratory investigations revealed hypokalemia, hypernatremia, and severe metabolic acidosis and anemia. Ultra-sound of the abdomen revealed enlarged kidneys without hydronerphrosis. The patient developed paralysis due to further decline in serum potassium level, which improved after an aggressive fluid and electrolyte management. He was investigated extensively for polyuria and type of acidosis. The kidney biopsy showed interstitial leukemic infiltration. He was managed accordingly and recovered from the condition. This case demonstrates an unusual presentation of a hematological malignancy, which was a diagnostic as well as a management challenge.http://www.sjkdt.org/article.asp?issn=1319-2442;year=2011;volume=22;issue=4;spage=847;epage=852;aulast=Imtiaz
spellingShingle Salman Imtiaz
Shahid Qayyum
Hala Kafouri
Habib ur Rehman
Mohammad Al Khoiter
Akram Askar
A young man with polyuria and lethargy
Saudi Journal of Kidney Diseases and Transplantation
title A young man with polyuria and lethargy
title_full A young man with polyuria and lethargy
title_fullStr A young man with polyuria and lethargy
title_full_unstemmed A young man with polyuria and lethargy
title_short A young man with polyuria and lethargy
title_sort young man with polyuria and lethargy
url http://www.sjkdt.org/article.asp?issn=1319-2442;year=2011;volume=22;issue=4;spage=847;epage=852;aulast=Imtiaz
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