A young man with polyuria and lethargy
We report a 20-year-old man who presented to our emergency room with a history of polyuria, weakness, constipation, nausea, and vomiting of two months duration. History and clinical examination revealed a significant weight loss and mild hepatomegaly. Laboratory investigations revealed hypokalemia,...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2011-01-01
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Series: | Saudi Journal of Kidney Diseases and Transplantation |
Online Access: | http://www.sjkdt.org/article.asp?issn=1319-2442;year=2011;volume=22;issue=4;spage=847;epage=852;aulast=Imtiaz |
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author | Salman Imtiaz Shahid Qayyum Hala Kafouri Habib ur Rehman Mohammad Al Khoiter Akram Askar |
author_facet | Salman Imtiaz Shahid Qayyum Hala Kafouri Habib ur Rehman Mohammad Al Khoiter Akram Askar |
author_sort | Salman Imtiaz |
collection | DOAJ |
description | We report a 20-year-old man who presented to our emergency room with a history of polyuria, weakness, constipation, nausea, and vomiting of two months duration. History and clinical examination revealed a significant weight loss and mild hepatomegaly. Laboratory investigations revealed hypokalemia, hypernatremia, and severe metabolic acidosis and anemia. Ultra-sound of the abdomen revealed enlarged kidneys without hydronerphrosis. The patient developed paralysis due to further decline in serum potassium level, which improved after an aggressive fluid and electrolyte management. He was investigated extensively for polyuria and type of acidosis. The kidney biopsy showed interstitial leukemic infiltration. He was managed accordingly and recovered from the condition. This case demonstrates an unusual presentation of a hematological malignancy, which was a diagnostic as well as a management challenge. |
first_indexed | 2024-04-12T08:54:09Z |
format | Article |
id | doaj.art-7c3f1fbca6e04256822caeca6475b667 |
institution | Directory Open Access Journal |
issn | 1319-2442 |
language | English |
last_indexed | 2024-04-12T08:54:09Z |
publishDate | 2011-01-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Saudi Journal of Kidney Diseases and Transplantation |
spelling | doaj.art-7c3f1fbca6e04256822caeca6475b6672022-12-22T03:39:28ZengWolters Kluwer Medknow PublicationsSaudi Journal of Kidney Diseases and Transplantation1319-24422011-01-01224847852A young man with polyuria and lethargySalman ImtiazShahid QayyumHala KafouriHabib ur RehmanMohammad Al KhoiterAkram AskarWe report a 20-year-old man who presented to our emergency room with a history of polyuria, weakness, constipation, nausea, and vomiting of two months duration. History and clinical examination revealed a significant weight loss and mild hepatomegaly. Laboratory investigations revealed hypokalemia, hypernatremia, and severe metabolic acidosis and anemia. Ultra-sound of the abdomen revealed enlarged kidneys without hydronerphrosis. The patient developed paralysis due to further decline in serum potassium level, which improved after an aggressive fluid and electrolyte management. He was investigated extensively for polyuria and type of acidosis. The kidney biopsy showed interstitial leukemic infiltration. He was managed accordingly and recovered from the condition. This case demonstrates an unusual presentation of a hematological malignancy, which was a diagnostic as well as a management challenge.http://www.sjkdt.org/article.asp?issn=1319-2442;year=2011;volume=22;issue=4;spage=847;epage=852;aulast=Imtiaz |
spellingShingle | Salman Imtiaz Shahid Qayyum Hala Kafouri Habib ur Rehman Mohammad Al Khoiter Akram Askar A young man with polyuria and lethargy Saudi Journal of Kidney Diseases and Transplantation |
title | A young man with polyuria and lethargy |
title_full | A young man with polyuria and lethargy |
title_fullStr | A young man with polyuria and lethargy |
title_full_unstemmed | A young man with polyuria and lethargy |
title_short | A young man with polyuria and lethargy |
title_sort | young man with polyuria and lethargy |
url | http://www.sjkdt.org/article.asp?issn=1319-2442;year=2011;volume=22;issue=4;spage=847;epage=852;aulast=Imtiaz |
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