Immunosuppressive effects of mesenchymal stem cells on lung B cell gene expression in LPS-induced acute lung injury

Immunosuppressive effects of mesenchymal stem cells on lung B cell gene expression in LPS-induced acute lung injury

Abstract Background Immune system disorders play important roles in acute lung injury (ALI), and mesenchymal stem cell (MSC) treatment can reduce inflammation during ALI. In this study, we compared the changes in lung B cells during MSC treatment. Methods We investigated the effects of MSCs on lung...

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Bibliographic Details
Main Authors: Bing Feng, Jiaqi Zhu, Yanping Xu, Wenyi Chen, Xinyu Sheng, Xudong Feng, Xiaowei Shi, Jingqi Liu, Qiaoling Pan, Jinfeng Yang, Jiong Yu, Lanjuan Li, Hongcui Cao
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stem cells
Lung B cells
Single-cell RNA sequencing
Acute lung injury
Online Access:http://link.springer.com/article/10.1186/s13287-020-01934-x

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