Deep learning-based multi-drug synergy prediction model for individually tailored anti-cancer therapies
While synergistic drug combinations are more effective at fighting tumors with complex pathophysiology, preference compensating mechanisms, and drug resistance, the identification of novel synergistic drug combinations, especially complex higher-order combinations, remains challenging due to the siz...
Main Authors: | Shengnan She, Hengwei Chen, Wei Ji, Mengqiu Sun, Jiaxi Cheng, Mengjie Rui, Chunlai Feng |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-12-01
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Series: | Frontiers in Pharmacology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2022.1032875/full |
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