Comparison of in vitro antioxidant properties of extracts from three plants used for medical purpose in Cameroon: Acalypha racemosa, Garcinia lucida and Hymenocardia lyrata
Objective: To investigate the in vitro antiradical and antioxidant properties of methanol extracts of Garcinia lucida, Hymenocardia lyrata (H. lyrata) and Acalypha racemosa. Methods: We determined the in vitro antioxidant activity and the total phenolic content, and performed the phytochemical scree...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2014-07-01
|
| Series: | Asian Pacific Journal of Tropical Biomedicine |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2221169115300617 |
| _version_ | 1818427673225986048 |
|---|---|
| author | Djacbou D. Sylvie Pieme Constant Anatole Biapa Prosper Cabral Penlap Beng Veronique |
| author_facet | Djacbou D. Sylvie Pieme Constant Anatole Biapa Prosper Cabral Penlap Beng Veronique |
| author_sort | Djacbou D. Sylvie |
| collection | DOAJ |
| description | Objective: To investigate the in vitro antiradical and antioxidant properties of methanol extracts of Garcinia lucida, Hymenocardia lyrata (H. lyrata) and Acalypha racemosa.
Methods: We determined the in vitro antioxidant activity and the total phenolic content, and performed the phytochemical screening of the extracts from fruits, barks, leaves, roots and stems of these plants using standard procedures.
Results: The results of the antioxidant properties showed that more than 60% of DPPH., NO. and HO. radicals were inhibited by the extracts. The radical scavenging activity, the total antioxidant capacity as well as the reducing power increased with the concentration of the extracts. The 50% inhibitory concentration (IC50) varied from 1.46 to 21.65 μg/mL depending of the type of extract and the antioxidant tests. The results indicated that all the extracts exhibited antioxidant properties and the roots of H. lyrata showed the best antioxidant activity [(217.17±9.45) mg Equivalent catechin/g of extract] while the highest total phenol content was found in its barks [(169.782±3.025) mg Eq cat/g of extract].
Conclusions: The methanol extract of H. lyrata possess the most antioxidant property among the three extracts. |
| first_indexed | 2024-12-14T14:49:28Z |
| format | Article |
| id | doaj.art-7c4beba597f74eafbfe32129a533bd39 |
| institution | Directory Open Access Journal |
| issn | 2221-1691 |
| language | English |
| last_indexed | 2024-12-14T14:49:28Z |
| publishDate | 2014-07-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Asian Pacific Journal of Tropical Biomedicine |
| spelling | doaj.art-7c4beba597f74eafbfe32129a533bd392022-12-21T22:57:11ZengWolters Kluwer Medknow PublicationsAsian Pacific Journal of Tropical Biomedicine2221-16912014-07-014S2S625S63210.12980/APJTB.4.201414B168Comparison of in vitro antioxidant properties of extracts from three plants used for medical purpose in Cameroon: Acalypha racemosa, Garcinia lucida and Hymenocardia lyrataDjacbou D. Sylvie0Pieme Constant Anatole1Biapa Prosper Cabral2Penlap Beng Veronique3Department of Biochemistry, University of Yaoundé I, PO Box 812, Yaoundé, CameroonFaculty of Medicine and Biomedical Sciences, University of Yaoundé I, PO Box 1364 Yaoundé, CameroonDepartment of Biochemistry, University of Dschang, Dschang, P.O Box 67 Dschang, CameroonDepartment of Biochemistry, University of Yaoundé I, PO Box 812, Yaoundé, CameroonObjective: To investigate the in vitro antiradical and antioxidant properties of methanol extracts of Garcinia lucida, Hymenocardia lyrata (H. lyrata) and Acalypha racemosa. Methods: We determined the in vitro antioxidant activity and the total phenolic content, and performed the phytochemical screening of the extracts from fruits, barks, leaves, roots and stems of these plants using standard procedures. Results: The results of the antioxidant properties showed that more than 60% of DPPH., NO. and HO. radicals were inhibited by the extracts. The radical scavenging activity, the total antioxidant capacity as well as the reducing power increased with the concentration of the extracts. The 50% inhibitory concentration (IC50) varied from 1.46 to 21.65 μg/mL depending of the type of extract and the antioxidant tests. The results indicated that all the extracts exhibited antioxidant properties and the roots of H. lyrata showed the best antioxidant activity [(217.17±9.45) mg Equivalent catechin/g of extract] while the highest total phenol content was found in its barks [(169.782±3.025) mg Eq cat/g of extract]. Conclusions: The methanol extract of H. lyrata possess the most antioxidant property among the three extracts.http://www.sciencedirect.com/science/article/pii/S2221169115300617AntioxidantsReducing powerFree radicalsPolyphenolsHymenocardia lyrataAcalypha racemosa |
| spellingShingle | Djacbou D. Sylvie Pieme Constant Anatole Biapa Prosper Cabral Penlap Beng Veronique Comparison of in vitro antioxidant properties of extracts from three plants used for medical purpose in Cameroon: Acalypha racemosa, Garcinia lucida and Hymenocardia lyrata Asian Pacific Journal of Tropical Biomedicine Antioxidants Reducing power Free radicals Polyphenols Hymenocardia lyrata Acalypha racemosa |
| title | Comparison of in vitro antioxidant properties of extracts from three plants used for medical purpose in Cameroon: Acalypha racemosa, Garcinia lucida and Hymenocardia lyrata |
| title_full | Comparison of in vitro antioxidant properties of extracts from three plants used for medical purpose in Cameroon: Acalypha racemosa, Garcinia lucida and Hymenocardia lyrata |
| title_fullStr | Comparison of in vitro antioxidant properties of extracts from three plants used for medical purpose in Cameroon: Acalypha racemosa, Garcinia lucida and Hymenocardia lyrata |
| title_full_unstemmed | Comparison of in vitro antioxidant properties of extracts from three plants used for medical purpose in Cameroon: Acalypha racemosa, Garcinia lucida and Hymenocardia lyrata |
| title_short | Comparison of in vitro antioxidant properties of extracts from three plants used for medical purpose in Cameroon: Acalypha racemosa, Garcinia lucida and Hymenocardia lyrata |
| title_sort | comparison of in vitro antioxidant properties of extracts from three plants used for medical purpose in cameroon acalypha racemosa garcinia lucida and hymenocardia lyrata |
| topic | Antioxidants Reducing power Free radicals Polyphenols Hymenocardia lyrata Acalypha racemosa |
| url | http://www.sciencedirect.com/science/article/pii/S2221169115300617 |
| work_keys_str_mv | AT djacboudsylvie comparisonofinvitroantioxidantpropertiesofextractsfromthreeplantsusedformedicalpurposeincameroonacalypharacemosagarcinialucidaandhymenocardialyrata AT piemeconstantanatole comparisonofinvitroantioxidantpropertiesofextractsfromthreeplantsusedformedicalpurposeincameroonacalypharacemosagarcinialucidaandhymenocardialyrata AT biapaprospercabral comparisonofinvitroantioxidantpropertiesofextractsfromthreeplantsusedformedicalpurposeincameroonacalypharacemosagarcinialucidaandhymenocardialyrata AT penlapbengveronique comparisonofinvitroantioxidantpropertiesofextractsfromthreeplantsusedformedicalpurposeincameroonacalypharacemosagarcinialucidaandhymenocardialyrata |