Relationship of pre-pandemic quality of life and avoiding vaccination against SARS-CoV-2 in patients with heart failure – a cohort study
Heart failure (HF) patients are vulnerable to a complicated course of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The aim of this research was to analyze the relationship between the decision not to be immunized against SARS-CoV-2, clinical, epidemiological factors and p...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Poznan University of Medical Sciences
2023-12-01
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| Series: | Journal of Medical Science |
| Subjects: | |
| Online Access: | https://jms.ump.edu.pl/index.php/JMS/article/view/883 |
| _version_ | 1827593142151413760 |
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| author | Filip Sawczak Agata Kukfisz Maria Cierzniak Alicja Szubarga Aleksandra Soloch Anita Balewska Magdalena Szczechla Helena Krysztofiak Katarzyna Przytarska Magdalena Dudek Izabella Uchmanowicz Ewa Straburzyńska-Migaj Marta Kałużna-Oleksy |
| author_facet | Filip Sawczak Agata Kukfisz Maria Cierzniak Alicja Szubarga Aleksandra Soloch Anita Balewska Magdalena Szczechla Helena Krysztofiak Katarzyna Przytarska Magdalena Dudek Izabella Uchmanowicz Ewa Straburzyńska-Migaj Marta Kałużna-Oleksy |
| author_sort | Filip Sawczak |
| collection | DOAJ |
| description |
Heart failure (HF) patients are vulnerable to a complicated course of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The aim of this research was to analyze the relationship between the decision not to be immunized against SARS-CoV-2, clinical, epidemiological factors and pre-pandemic health-related quality of life (HRQoL) of HF patients . Prior to the onset of the SARS-CoV-2 pandemic, hospitalized HF patients were enrolled as a prospective cohort and interviewed with World Health Organization Quality of Life Brief Version questionnaire. On October 30, 2021, the immunization status was verified. The association of vaccination hesitancy with epidemiological and clinical parameters, and pre-pandemic questionnaire results was tested. Subsequently, the independence from confounding factors, age, sex, New York Heart Association (NYHA) scale, and left ventricular ejection fraction (LVEF) was analyzed. Among 136 included patients, 77.9% were vaccinated. Unvaccinated patients were younger (51.2±13.2 vs 56.6±10.3; p=0.018) and more frequently had non-ischemic etiology of HF (73.3% vs. 46.7%; p=0.013). It was significant after adjustment for age, sex, NYHA class and LVEF. There was no association of overall HRQoL or domain scores with vaccination status. Younger age as a factor associated with vaccine avoidance in this population is consistent with data from the general population despite higher exposure to the severe course of the disease.
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| first_indexed | 2024-03-09T02:05:46Z |
| format | Article |
| id | doaj.art-7c4c2a21798c484eb5bbf89edb6c2af7 |
| institution | Directory Open Access Journal |
| issn | 2353-9798 2353-9801 |
| language | English |
| last_indexed | 2024-03-09T02:05:46Z |
| publishDate | 2023-12-01 |
| publisher | Poznan University of Medical Sciences |
| record_format | Article |
| series | Journal of Medical Science |
| spelling | doaj.art-7c4c2a21798c484eb5bbf89edb6c2af72023-12-07T17:26:36ZengPoznan University of Medical SciencesJournal of Medical Science2353-97982353-98012023-12-0110.20883/medical.e883Relationship of pre-pandemic quality of life and avoiding vaccination against SARS-CoV-2 in patients with heart failure – a cohort studyFilip Sawczak0https://orcid.org/0000-0003-3449-8751Agata Kukfisz1https://orcid.org/0000-0001-9424-8004Maria Cierzniak2https://orcid.org/0000-0002-1881-5086Alicja Szubarga3https://orcid.org/0000-0002-6215-7148Aleksandra Soloch4https://orcid.org/0000-0002-7410-190XAnita Balewskahttps://orcid.org/0000-0001-7472-478XMagdalena Szczechla5https://orcid.org/0000-0002-7307-4460Helena Krysztofiak6https://orcid.org/0000-0003-0748-9059Katarzyna Przytarska 7https://orcid.org/0000-0001-6985-3640Magdalena Dudek8https://orcid.org/0000-0001-6550-6182Izabella Uchmanowicz9https://orcid.org/0000-0001-5452-0210Ewa Straburzyńska-Migaj 10https://orcid.org/0000-0002-0545-3370Marta Kałużna-Oleksy11https://orcid.org/0000-0003-4048-62471st Department of Cardiology, Poznan University of Medical Sciences, Poznan, Poland1 st Department of Cardiology, Poznan University of Medical Sciences, Poznan, Poland,1st Department of Cardiology, Poznan University of Medical Sciences, Poznan, Poland1st Department of Cardiology, Poznan University of Medical Sciences, Poznan, Poland1st Department of Cardiology, Poznan University of Medical Sciences, Poznan, Poland1st Department of Cardiology, Poznan University of Medical Sciences, Poznan, PolandDepartment of Cardiology, University Hospital in Opole, Opole, Poland,1st Department of Cardiology, Poznan University of Medical Sciences, Poznan, Poland1st Department of Cardiology, Poznan University of Medical Sciences, Poznan, PolandFaculty of Health Sciences, Wroclaw Medical University, Wroclaw, Poland1st Department of Cardiology, Poznan University of Medical Sciences, Poznan, Poland1 st Department of Cardiology, Poznan University of Medical Sciences, Poznan, Poland, Heart failure (HF) patients are vulnerable to a complicated course of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The aim of this research was to analyze the relationship between the decision not to be immunized against SARS-CoV-2, clinical, epidemiological factors and pre-pandemic health-related quality of life (HRQoL) of HF patients . Prior to the onset of the SARS-CoV-2 pandemic, hospitalized HF patients were enrolled as a prospective cohort and interviewed with World Health Organization Quality of Life Brief Version questionnaire. On October 30, 2021, the immunization status was verified. The association of vaccination hesitancy with epidemiological and clinical parameters, and pre-pandemic questionnaire results was tested. Subsequently, the independence from confounding factors, age, sex, New York Heart Association (NYHA) scale, and left ventricular ejection fraction (LVEF) was analyzed. Among 136 included patients, 77.9% were vaccinated. Unvaccinated patients were younger (51.2±13.2 vs 56.6±10.3; p=0.018) and more frequently had non-ischemic etiology of HF (73.3% vs. 46.7%; p=0.013). It was significant after adjustment for age, sex, NYHA class and LVEF. There was no association of overall HRQoL or domain scores with vaccination status. Younger age as a factor associated with vaccine avoidance in this population is consistent with data from the general population despite higher exposure to the severe course of the disease. https://jms.ump.edu.pl/index.php/JMS/article/view/883COVID-19quality of lifeheart failurevaccinationvaccination hesitancycardiovascular disease |
| spellingShingle | Filip Sawczak Agata Kukfisz Maria Cierzniak Alicja Szubarga Aleksandra Soloch Anita Balewska Magdalena Szczechla Helena Krysztofiak Katarzyna Przytarska Magdalena Dudek Izabella Uchmanowicz Ewa Straburzyńska-Migaj Marta Kałużna-Oleksy Relationship of pre-pandemic quality of life and avoiding vaccination against SARS-CoV-2 in patients with heart failure – a cohort study Journal of Medical Science COVID-19 quality of life heart failure vaccination vaccination hesitancy cardiovascular disease |
| title | Relationship of pre-pandemic quality of life and avoiding vaccination against SARS-CoV-2 in patients with heart failure – a cohort study |
| title_full | Relationship of pre-pandemic quality of life and avoiding vaccination against SARS-CoV-2 in patients with heart failure – a cohort study |
| title_fullStr | Relationship of pre-pandemic quality of life and avoiding vaccination against SARS-CoV-2 in patients with heart failure – a cohort study |
| title_full_unstemmed | Relationship of pre-pandemic quality of life and avoiding vaccination against SARS-CoV-2 in patients with heart failure – a cohort study |
| title_short | Relationship of pre-pandemic quality of life and avoiding vaccination against SARS-CoV-2 in patients with heart failure – a cohort study |
| title_sort | relationship of pre pandemic quality of life and avoiding vaccination against sars cov 2 in patients with heart failure a cohort study |
| topic | COVID-19 quality of life heart failure vaccination vaccination hesitancy cardiovascular disease |
| url | https://jms.ump.edu.pl/index.php/JMS/article/view/883 |
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