Virus-like Silica Nanoparticles Improve Permeability of Macromolecules across the Blood–Brain Barrier In Vitro

Virus-like Silica Nanoparticles Improve Permeability of Macromolecules across the Blood–Brain Barrier In Vitro

The presence of the blood–brain barrier (BBB) limits the delivery of therapies into the brain. There has been significant interest in overcoming the BBB for the effective delivery of therapies to the brain. Inorganic nanomaterials, especially silica nanoparticles with varying surface chemistry and s...

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Bibliographic Details
Main Authors: Yuran Feng, Yuxue Cao, Zhi Qu, Taskeen Iqbal Janjua, Amirali Popat
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Pharmaceutics
Subjects:
virus-like silica nanoparticles
blood–brain barrier
brain drug delivery
glioblastoma
surface roughness
Online Access:https://www.mdpi.com/1999-4923/15/9/2239

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