BRAF<sup>V600E</sup> Expression in Thyrocytes Causes Recruitment of Immunosuppressive STABILIN-1 Macrophages

BRAF<sup>V600E</sup> Expression in Thyrocytes Causes Recruitment of Immunosuppressive STABILIN-1 Macrophages

Papillary thyroid carcinoma (PTC) is the most frequent histological subtype of thyroid cancers (TC), and BRAF<sup>V600E</sup> genetic alteration is found in 60% of this endocrine cancer. This oncogene is associated with poor prognosis, resistance to radioiodine therapy, and tumor progres...

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Bibliographic Details
Main Authors: Catherine Spourquet, Ophélie Delcorte, Pascale Lemoine, Nicolas Dauguet, Axelle Loriot, Younes Achouri, Maija Hollmén, Sirpa Jalkanen, François Huaux, Sophie Lucas, Pierre Van Meerkeeck, Jeffrey A. Knauf, James A. Fagin, Chantal Dessy, Michel Mourad, Patrick Henriet, Donatienne Tyteca, Etienne Marbaix, Christophe E. Pierreux
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cancers
Subjects:
<i>Stab1</i><sup>−/−</sup> mice
CD4/CD8 T cells
thyroid diseases
Online Access:https://www.mdpi.com/2072-6694/14/19/4687

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