In vitro inhibitory effects of Friedelin on human liver cytochrome P450 enzymes

In vitro inhibitory effects of Friedelin on human liver cytochrome P450 enzymes

Context: Friedelin is a triterpenoid with several biological activities. However, the affects of Friedelin on the activity of human liver cytochrome P450 (CYP) enzymes remains unclear. Objective: This study investigates the inhibitory effects of Friedelin on the major human liver CYP isoforms (CYP3A...

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Bibliographic Details
Main Authors: Jinlan Wei, Hongying Zhang, Qingling Zhao
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Pharmaceutical Biology
Subjects:
cyp3a4
cyp2e1
drug–drug interactions
Online Access:http://dx.doi.org/10.1080/13880209.2018.1491999

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