An Exponential Regression Model Reveals the Continuous Development of B Cell Subpopulations Used as Reference Values in Children

An Exponential Regression Model Reveals the Continuous Development of B Cell Subpopulations Used as Reference Values in Children

B lymphocytes are key players in humoral immunity, expressing diverse surface immunoglobulin receptors directed against specific antigenic epitopes. The development and profile of distinct subpopulations have gained awareness in the setting of primary immunodeficiency disorders, primary or secondary...

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Bibliographic Details
Main Authors: Christoph Königs, Stephan Schultze-Strasser, Andrea Quaiser, Konrad Bochennek, Dirk Schwabe, Thomas E. Klingebiel, Ulrike Koehl, Claudia Cappel, Udo Rolle, Peter Bader, Melanie Bremm, Sabine Huenecke, Shahrzad Bakhtiar
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Pediatrics
Subjects:
B cell subpopulations
reference values
exponential model
autoimmunity
flow cytometry
Online Access:http://journal.frontiersin.org/article/10.3389/fped.2018.00121/full

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