Heparin-coated vs. Non-coated Cardiopulmonary Bypass Circuits: Comparing Immediate Results with Different Target Activated Clotting Time
Abstract Objective: To compare immediate postoperative results in patients receiving heparin-albumin-coated and non-coated circuits. Methods: A total of 241 patients undergoing on-pump cardiac surgery were divided into two groups: those receiving heparin-coated circuits (Bioline®, Maquet Cardiopul...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Cirurgia Cardiovascular
2020-06-01
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| Series: | Brazilian Journal of Cardiovascular Surgery |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382020000600913&tlng=en |
| _version_ | 1811246429653434368 |
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| author | Muhammet Onur Hanedan Mehmet Ali Yürük Ali Kemal Arslan Aşkın Kılıç Ufuk Sayar İlker Mataracı |
| author_facet | Muhammet Onur Hanedan Mehmet Ali Yürük Ali Kemal Arslan Aşkın Kılıç Ufuk Sayar İlker Mataracı |
| author_sort | Muhammet Onur Hanedan |
| collection | DOAJ |
| description | Abstract Objective: To compare immediate postoperative results in patients receiving heparin-albumin-coated and non-coated circuits. Methods: A total of 241 patients undergoing on-pump cardiac surgery were divided into two groups: those receiving heparin-coated circuits (Bioline®, Maquet Cardiopulmonary AG., Hirrlingen, Germany) and those receiving non-coated circuits (Maquet Cardiopulmonary AG., Hirrlingen, Germany). Results: Activated clotting times (ACT) during cardiopulmonary bypass (CPB) were significantly shorter in the heparin-albumin-coated group than in the non-coated group (355.64±34.12 vs. 560.38±90.20, respectively, P=0.001). In-hospital mortality and postoperative stroke rates and lengths of intensive care unit stay were similar between the groups; in contrast, in the heparin-albumin-coated group, patients had significantly better outcomes for hospital stay, drainage, and need for erythrocyte transfusion. Conclusion: Heparin-coated circuits and reduced level of systemic heparinization with 300 seconds of target ACT level in cardiac surgery under CPB are safe and result in a very satisfactory clinical course. |
| first_indexed | 2024-04-12T14:54:27Z |
| format | Article |
| id | doaj.art-7c57bf2c95074ec1b2aadb5c6650e080 |
| institution | Directory Open Access Journal |
| issn | 1678-9741 |
| language | English |
| last_indexed | 2024-04-12T14:54:27Z |
| publishDate | 2020-06-01 |
| publisher | Sociedade Brasileira de Cirurgia Cardiovascular |
| record_format | Article |
| series | Brazilian Journal of Cardiovascular Surgery |
| spelling | doaj.art-7c57bf2c95074ec1b2aadb5c6650e0802022-12-22T03:28:19ZengSociedade Brasileira de Cirurgia CardiovascularBrazilian Journal of Cardiovascular Surgery1678-97412020-06-0135691391710.21470/1678-9741-2019-0387Heparin-coated vs. Non-coated Cardiopulmonary Bypass Circuits: Comparing Immediate Results with Different Target Activated Clotting TimeMuhammet Onur Hanedanhttps://orcid.org/0000-0002-8363-7861Mehmet Ali YürükAli Kemal ArslanAşkın KılıçUfuk Sayarİlker MataracıAbstract Objective: To compare immediate postoperative results in patients receiving heparin-albumin-coated and non-coated circuits. Methods: A total of 241 patients undergoing on-pump cardiac surgery were divided into two groups: those receiving heparin-coated circuits (Bioline®, Maquet Cardiopulmonary AG., Hirrlingen, Germany) and those receiving non-coated circuits (Maquet Cardiopulmonary AG., Hirrlingen, Germany). Results: Activated clotting times (ACT) during cardiopulmonary bypass (CPB) were significantly shorter in the heparin-albumin-coated group than in the non-coated group (355.64±34.12 vs. 560.38±90.20, respectively, P=0.001). In-hospital mortality and postoperative stroke rates and lengths of intensive care unit stay were similar between the groups; in contrast, in the heparin-albumin-coated group, patients had significantly better outcomes for hospital stay, drainage, and need for erythrocyte transfusion. Conclusion: Heparin-coated circuits and reduced level of systemic heparinization with 300 seconds of target ACT level in cardiac surgery under CPB are safe and result in a very satisfactory clinical course.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382020000600913&tlng=enCardiopulmonary BypassHeparinHospital MortalityLength of StayErythrocyte TransfusionSilverCardiac Surgical ProceduresIntensive Care UnitsPostoperative Period |
| spellingShingle | Muhammet Onur Hanedan Mehmet Ali Yürük Ali Kemal Arslan Aşkın Kılıç Ufuk Sayar İlker Mataracı Heparin-coated vs. Non-coated Cardiopulmonary Bypass Circuits: Comparing Immediate Results with Different Target Activated Clotting Time Brazilian Journal of Cardiovascular Surgery Cardiopulmonary Bypass Heparin Hospital Mortality Length of Stay Erythrocyte Transfusion Silver Cardiac Surgical Procedures Intensive Care Units Postoperative Period |
| title | Heparin-coated vs. Non-coated Cardiopulmonary Bypass Circuits: Comparing Immediate Results with Different Target Activated Clotting Time |
| title_full | Heparin-coated vs. Non-coated Cardiopulmonary Bypass Circuits: Comparing Immediate Results with Different Target Activated Clotting Time |
| title_fullStr | Heparin-coated vs. Non-coated Cardiopulmonary Bypass Circuits: Comparing Immediate Results with Different Target Activated Clotting Time |
| title_full_unstemmed | Heparin-coated vs. Non-coated Cardiopulmonary Bypass Circuits: Comparing Immediate Results with Different Target Activated Clotting Time |
| title_short | Heparin-coated vs. Non-coated Cardiopulmonary Bypass Circuits: Comparing Immediate Results with Different Target Activated Clotting Time |
| title_sort | heparin coated vs non coated cardiopulmonary bypass circuits comparing immediate results with different target activated clotting time |
| topic | Cardiopulmonary Bypass Heparin Hospital Mortality Length of Stay Erythrocyte Transfusion Silver Cardiac Surgical Procedures Intensive Care Units Postoperative Period |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382020000600913&tlng=en |
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