Emergence of Novel Coronavirus 2019-nCoV: Need for Rapid Vaccine and Biologics Development
Novel Coronavirus (2019-nCoV) is an emerging pathogen that was first identified in Wuhan, China in late December 2019. This virus is responsible for the ongoing outbreak that causes severe respiratory illness and pneumonia-like infection in humans. Due to the increasing number of cases in China and...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-02-01
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| Series: | Pathogens |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-0817/9/2/148 |
| _version_ | 1798035319159783424 |
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| author | Balamurugan Shanmugaraj Ashwini Malla Waranyoo Phoolcharoen |
| author_facet | Balamurugan Shanmugaraj Ashwini Malla Waranyoo Phoolcharoen |
| author_sort | Balamurugan Shanmugaraj |
| collection | DOAJ |
| description | Novel Coronavirus (2019-nCoV) is an emerging pathogen that was first identified in Wuhan, China in late December 2019. This virus is responsible for the ongoing outbreak that causes severe respiratory illness and pneumonia-like infection in humans. Due to the increasing number of cases in China and outside China, the WHO declared coronavirus as a global health emergency. Nearly 35,000 cases were reported and at least 24 other countries or territories have reported coronavirus cases as early on as February. Inter-human transmission was reported in a few countries, including the United States. Neither an effective anti-viral nor a vaccine is currently available to treat this infection. As the virus is a newly emerging pathogen, many questions remain unanswered regarding the virus’s reservoirs, pathogenesis, transmissibility, and much more is unknown. The collaborative efforts of researchers are needed to fill the knowledge gaps about this new virus, to develop the proper diagnostic tools, and effective treatment to combat this infection. Recent advancements in plant biotechnology proved that plants have the ability to produce vaccines or biopharmaceuticals rapidly in a short time. In this review, the outbreak of 2019-nCoV in China, the need for rapid vaccine development, and the potential of a plant system for biopharmaceutical development are discussed. |
| first_indexed | 2024-04-11T20:56:35Z |
| format | Article |
| id | doaj.art-7c5b4bf6d0cd4e81b96f453900df4cce |
| institution | Directory Open Access Journal |
| issn | 2076-0817 |
| language | English |
| last_indexed | 2024-04-11T20:56:35Z |
| publishDate | 2020-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pathogens |
| spelling | doaj.art-7c5b4bf6d0cd4e81b96f453900df4cce2022-12-22T04:03:40ZengMDPI AGPathogens2076-08172020-02-019214810.3390/pathogens9020148pathogens9020148Emergence of Novel Coronavirus 2019-nCoV: Need for Rapid Vaccine and Biologics DevelopmentBalamurugan Shanmugaraj0Ashwini Malla1Waranyoo Phoolcharoen2Research unit for Plant-produced Pharmaceuticals, Chulalongkorn University, Bangkok 10330, ThailandResearch unit for Plant-produced Pharmaceuticals, Chulalongkorn University, Bangkok 10330, ThailandResearch unit for Plant-produced Pharmaceuticals, Chulalongkorn University, Bangkok 10330, ThailandNovel Coronavirus (2019-nCoV) is an emerging pathogen that was first identified in Wuhan, China in late December 2019. This virus is responsible for the ongoing outbreak that causes severe respiratory illness and pneumonia-like infection in humans. Due to the increasing number of cases in China and outside China, the WHO declared coronavirus as a global health emergency. Nearly 35,000 cases were reported and at least 24 other countries or territories have reported coronavirus cases as early on as February. Inter-human transmission was reported in a few countries, including the United States. Neither an effective anti-viral nor a vaccine is currently available to treat this infection. As the virus is a newly emerging pathogen, many questions remain unanswered regarding the virus’s reservoirs, pathogenesis, transmissibility, and much more is unknown. The collaborative efforts of researchers are needed to fill the knowledge gaps about this new virus, to develop the proper diagnostic tools, and effective treatment to combat this infection. Recent advancements in plant biotechnology proved that plants have the ability to produce vaccines or biopharmaceuticals rapidly in a short time. In this review, the outbreak of 2019-nCoV in China, the need for rapid vaccine development, and the potential of a plant system for biopharmaceutical development are discussed.https://www.mdpi.com/2076-0817/9/2/148biopharmaceuticalscoronavirusemerging threatinfectious diseasesplant systemtransient expressionviruseszoonoses |
| spellingShingle | Balamurugan Shanmugaraj Ashwini Malla Waranyoo Phoolcharoen Emergence of Novel Coronavirus 2019-nCoV: Need for Rapid Vaccine and Biologics Development Pathogens biopharmaceuticals coronavirus emerging threat infectious diseases plant system transient expression viruses zoonoses |
| title | Emergence of Novel Coronavirus 2019-nCoV: Need for Rapid Vaccine and Biologics Development |
| title_full | Emergence of Novel Coronavirus 2019-nCoV: Need for Rapid Vaccine and Biologics Development |
| title_fullStr | Emergence of Novel Coronavirus 2019-nCoV: Need for Rapid Vaccine and Biologics Development |
| title_full_unstemmed | Emergence of Novel Coronavirus 2019-nCoV: Need for Rapid Vaccine and Biologics Development |
| title_short | Emergence of Novel Coronavirus 2019-nCoV: Need for Rapid Vaccine and Biologics Development |
| title_sort | emergence of novel coronavirus 2019 ncov need for rapid vaccine and biologics development |
| topic | biopharmaceuticals coronavirus emerging threat infectious diseases plant system transient expression viruses zoonoses |
| url | https://www.mdpi.com/2076-0817/9/2/148 |
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