Transient increase in cyclic AMP localized to macrophage phagosomes.

Transient increase in cyclic AMP localized to macrophage phagosomes.

Cyclic AMP (cAMP) regulates many biological processes and cellular functions. The importance of spatially localized intracellular gradients of cAMP is increasingly appreciated. Previous work in macrophages has shown that cAMP is produced during phagocytosis and that elevated cAMP levels suppress hos...

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Bibliographic Details
Main Authors: Megan N Ballinger, Timothy Welliver, Samuel Straight, Marc Peters-Golden, Joel A Swanson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2978719?pdf=render

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