Baculovirus Utilizes Cholesterol Transporter NIEMANN–Pick C1 for Host Cell Entry

Baculovirus Utilizes Cholesterol Transporter NIEMANN–Pick C1 for Host Cell Entry

The dual roles of baculovirus for the control of natural insect populations as an insecticide, and as a tool for foreign gene expression and delivery, have called for a comprehensive understanding of the molecular mechanisms governing viral infection. Here, we demonstrate that the Bombyx mori Nieman...

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Bibliographic Details
Main Authors: Zhihong Li, Youpeng Fan, Junhong Wei, Xionge Mei, Qiang He, Yonghua Zhang, Tian Li, Mengxian Long, Jie Chen, Jialing Bao, Guoqing Pan, Chunfeng Li, Zeyang Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Microbiology
Subjects:
Bombyx mori
BmNPV
NPC1
cholesterol trafficking pathway
enveloped virus
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02825/full

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