Novel oxygen saturation imaging endoscopy to assess anastomotic integrity in a porcine ischemia model
Abstract Background Establishing anastomotic integrity is crucial for avoiding anastomotic complications in colorectal surgery. This study aimed to evaluate the safety and feasibility of assessing anastomotic integrity using novel oxygen saturation imaging endoscopy in a porcine ischemia model. Meth...
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| Format: | Article |
| Language: | English |
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BMC
2020-10-01
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| Series: | BMC Surgery |
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| Online Access: | http://link.springer.com/article/10.1186/s12893-020-00913-6 |
| _version_ | 1818288944835461120 |
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| author | Hiro Hasegawa Nobuyoshi Takeshita Masaaki Ito |
| author_facet | Hiro Hasegawa Nobuyoshi Takeshita Masaaki Ito |
| author_sort | Hiro Hasegawa |
| collection | DOAJ |
| description | Abstract Background Establishing anastomotic integrity is crucial for avoiding anastomotic complications in colorectal surgery. This study aimed to evaluate the safety and feasibility of assessing anastomotic integrity using novel oxygen saturation imaging endoscopy in a porcine ischemia model. Methods In three pigs, a new endoscope system was used to check the mechanical completeness of the anastomosis and capture the tissue oxygen saturation (StO2) images. This technology can derive the StO2 images from the differences in the absorption coefficient in the visible light region between oxy- and deoxy-hemoglobin. Bowel perfusion at the proximal rectum was assessed before and after the anastomosis, and 1 min and 30 min after the ligation of the cranial rectal artery (CRA). Results The completeness of the anastomoses was confirmed by the absence of air leakage. Intraluminal oxygen saturation imaging was successfully performed in all animals. There was no significant difference in the StO2 level before and after the anastomosis (52.6 ± 2.0 vs. 52.0 ± 2.6; p = 0.76, respectively). The StO2 level of the intestine on the oral side of the anastomosis one minute after the CRA ligation was significantly lower than immediately after the anastomosis (15.9 ± 6.0 vs. 52.0 ± 2.6; p = 0.006, respectively). There was no significant difference in the StO2 level between 1 min after and 30 min after the CRA ligation (15.9 ± 6.0 vs. 12.1 ± 5.3; p = 0.41, respectively). Conclusion Novel oxygen saturation imaging endoscopy was safe and feasible to assess the anastomotic integrity in the experimental model. |
| first_indexed | 2024-12-13T02:04:26Z |
| format | Article |
| id | doaj.art-7c6b39b90feb4fc29e12eb42aa0de6fa |
| institution | Directory Open Access Journal |
| issn | 1471-2482 |
| language | English |
| last_indexed | 2024-12-13T02:04:26Z |
| publishDate | 2020-10-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Surgery |
| spelling | doaj.art-7c6b39b90feb4fc29e12eb42aa0de6fa2022-12-22T00:03:11ZengBMCBMC Surgery1471-24822020-10-012011810.1186/s12893-020-00913-6Novel oxygen saturation imaging endoscopy to assess anastomotic integrity in a porcine ischemia modelHiro Hasegawa0Nobuyoshi Takeshita1Masaaki Ito2Department of Colorectal Surgery, National Cancer Center Hospital EastDepartment of Colorectal Surgery, National Cancer Center Hospital EastDepartment of Colorectal Surgery, National Cancer Center Hospital EastAbstract Background Establishing anastomotic integrity is crucial for avoiding anastomotic complications in colorectal surgery. This study aimed to evaluate the safety and feasibility of assessing anastomotic integrity using novel oxygen saturation imaging endoscopy in a porcine ischemia model. Methods In three pigs, a new endoscope system was used to check the mechanical completeness of the anastomosis and capture the tissue oxygen saturation (StO2) images. This technology can derive the StO2 images from the differences in the absorption coefficient in the visible light region between oxy- and deoxy-hemoglobin. Bowel perfusion at the proximal rectum was assessed before and after the anastomosis, and 1 min and 30 min after the ligation of the cranial rectal artery (CRA). Results The completeness of the anastomoses was confirmed by the absence of air leakage. Intraluminal oxygen saturation imaging was successfully performed in all animals. There was no significant difference in the StO2 level before and after the anastomosis (52.6 ± 2.0 vs. 52.0 ± 2.6; p = 0.76, respectively). The StO2 level of the intestine on the oral side of the anastomosis one minute after the CRA ligation was significantly lower than immediately after the anastomosis (15.9 ± 6.0 vs. 52.0 ± 2.6; p = 0.006, respectively). There was no significant difference in the StO2 level between 1 min after and 30 min after the CRA ligation (15.9 ± 6.0 vs. 12.1 ± 5.3; p = 0.41, respectively). Conclusion Novel oxygen saturation imaging endoscopy was safe and feasible to assess the anastomotic integrity in the experimental model.http://link.springer.com/article/10.1186/s12893-020-00913-6Anastomotic integrityEndoscopyPerfusion assessmentTissue oxygen saturation |
| spellingShingle | Hiro Hasegawa Nobuyoshi Takeshita Masaaki Ito Novel oxygen saturation imaging endoscopy to assess anastomotic integrity in a porcine ischemia model BMC Surgery Anastomotic integrity Endoscopy Perfusion assessment Tissue oxygen saturation |
| title | Novel oxygen saturation imaging endoscopy to assess anastomotic integrity in a porcine ischemia model |
| title_full | Novel oxygen saturation imaging endoscopy to assess anastomotic integrity in a porcine ischemia model |
| title_fullStr | Novel oxygen saturation imaging endoscopy to assess anastomotic integrity in a porcine ischemia model |
| title_full_unstemmed | Novel oxygen saturation imaging endoscopy to assess anastomotic integrity in a porcine ischemia model |
| title_short | Novel oxygen saturation imaging endoscopy to assess anastomotic integrity in a porcine ischemia model |
| title_sort | novel oxygen saturation imaging endoscopy to assess anastomotic integrity in a porcine ischemia model |
| topic | Anastomotic integrity Endoscopy Perfusion assessment Tissue oxygen saturation |
| url | http://link.springer.com/article/10.1186/s12893-020-00913-6 |
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