PLEK2 promotes cancer stemness and tumorigenesis of head and neck squamous cell carcinoma via the c‐Myc‐mediated positive feedback loop

PLEK2 promotes cancer stemness and tumorigenesis of head and neck squamous cell carcinoma via the c‐Myc‐mediated positive feedback loop

Abstract Background Head and neck squamous cell carcinoma (HNSCC) is one of the most frequent malignancies worldwide and is characterized by unfavorable prognosis, high lymph node metastasis and early recurrence. However, the molecular events regulating HNSCC tumorigenesis remain poorly understood....

Full description

Bibliographic Details
Main Authors: Xinyuan Zhao, Dalong Shu, Wenjuan Sun, Shanshan Si, Wei Ran, Bing Guo, Li Cui
Format: Article
Language:English
Published: Wiley 2022-10-01
Series:Cancer Communications
Subjects:
c‐Myc
cancer stemness
FBXW7
HNSCC
PLEK2
positive feedback loop
Online Access:https://doi.org/10.1002/cac2.12349

Similar Items

Similar Items