The Bartonella autotransporter BafA activates the host VEGF pathway to drive angiogenesis
Pathogenic bacteria of the genus Bartonella can induce vasoproliferative lesions during infection. Here, Tsukamoto et al. show that this effect is caused by a secreted protein that induces cell proliferation and angiogenesis by acting as an analog of the host’s vascular endothelial growth factor (VE...
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Bibliographic Details
| Main Authors: |
Kentaro Tsukamoto,
Naoaki Shinzawa,
Akito Kawai,
Masahiro Suzuki,
Hiroyasu Kidoya,
Nobuyuki Takakura,
Hisateru Yamaguchi,
Toshiki Kameyama,
Hidehito Inagaki,
Hiroki Kurahashi,
Yasuhiko Horiguchi,
Yohei Doi |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2020-07-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-020-17391-2
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