Quinolinic Acid and Nuclear Factor Erythroid 2-Related Factor 2 in Depression: Role in Neuroprogression

Quinolinic Acid and Nuclear Factor Erythroid 2-Related Factor 2 in Depression: Role in Neuroprogression

Depression is an incapacitating neuropsychiatric disorder. The serotonergic system in the brain plays an important role in the pathophysiology of depression. However, due to delayed and/or poor performance of selective serotonin reuptake inhibitors in treating depressive symptoms, the role of the se...

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Bibliographic Details
Main Authors: Yashika Bansal, Raghunath Singh, Ishwar Parhar, Anurag Kuhad, Tomoko Soga
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Pharmacology
Subjects:
oxidative stress
depression
serotonin
quinolinic acid
tryptophan
Nrf2
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00452/full

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