Novel bimodal TRBD1-TRBD2 rearrangements with dual or absent D-region contribute to TRB V-(D)-J combinatorial diversity
T-cell receptor (TR) diversity of the variable domains is generated by recombination of both the alpha (TRA) and beta (TRB) chains. The textbook process of TRB chain production starts with TRBD and TRBJ gene rearrangement, followed by the rearrangement of a TRBV gene to the partially rearranged D-J...
| Main Authors: | , , , , , , , |
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| 格式: | 文件 |
| 语言: | English |
| 出版: |
Frontiers Media S.A.
2023-09-01
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| 丛编: | Frontiers in Immunology |
| 主题: | |
| 在线阅读: | https://www.frontiersin.org/articles/10.3389/fimmu.2023.1245175/full |