The Finely Coordinated Action of SSB and NurA/HerA Complex Strictly Regulates the DNA End Resection Process in <i>Saccharolobus solfataricus</i>

The Finely Coordinated Action of SSB and NurA/HerA Complex Strictly Regulates the DNA End Resection Process in <i>Saccharolobus solfataricus</i>

Generation of the 3′ overhang is a critical step during homologous recombination (HR) and replication fork rescue processes. This event is usually performed by a series of DNA nucleases and/or helicases. The nuclease NurA and the ATPase HerA, together with the highly conserved MRE11/RAD50 proteins,...

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Bibliographic Details
Main Authors: Mariarosaria De Falco, Alessandra Porritiello, Federica Rota, Viviana Scognamiglio, Amina Antonacci, Giovanni del Monaco, Mariarita De Felice
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:International Journal of Molecular Sciences
Subjects:
DNA repair
HR
nuclease
DNA helicase
SSB
Archaea
Online Access:https://www.mdpi.com/1422-0067/23/5/2582

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