Frequency and Association of SNP rs 8111989 in CKMM A/G Gene in Weightlifting Men with Non-Athlete Men
Introduction: Genetic factors affect physical performance, exercise response, as well as elite athletic status; Therefore, the aim of the present study was the investigation of the Frequency and association of SNP rs 8111989 in CKMM A/G gene in weightlifting men with non-athlete men. Material &...
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| Format: | Article |
| Language: | fas |
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Ilam University of Medical Sciences
2022-08-01
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| Series: | Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām |
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| Online Access: | http://sjimu.medilam.ac.ir/article-1-7441-en.html |
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| author | Fateme Hashemzade ghodaneh Mohammad Reza Batavani Mohsen Ghofrani |
| author_facet | Fateme Hashemzade ghodaneh Mohammad Reza Batavani Mohsen Ghofrani |
| author_sort | Fateme Hashemzade ghodaneh |
| collection | DOAJ |
| description | Introduction: Genetic factors affect physical performance, exercise response, as well as elite athletic status; Therefore, the aim of the present study was the investigation of the Frequency and association of SNP rs 8111989 in CKMM A/G gene in weightlifting men with non-athlete men.
Material & Methods: In this descriptive study, the subjects were include of all (n=30) elite male weightlifters (league champions, members of national team, and the champions of Asian, world and Olympics) from Isfahan province, age: 21.77±7.11; Height: 179.87±6.98 and weight: 96.87±22.73 (mean±standard deviation) Which compared with 44 non-athletes with similar anthropometric (age, height and weight) characteristics. 4 cc saliva samples were collected from each subject and After DNA extraction, the allelic and genotypic prevalence of CKMM A/G gene was determined by PCR via RFLP and electrophoresis. Independent t-test, chi-square and logistic regression were used to analyze the data via the SPSS software version 20. Also the significance level was considered at P<0.05.
Findings: The results showed that the prevalence of AG genotype was significantly higher than AA and GG genotypes in weightlifting, non-athlete and total population groups (P <0.05). Also, there was no significant relationship between CKMM A/G genotype and weightlifting status and there was no significant difference between weightlifters and non-athletes (P >0.05).
Discussion & Conclusion: The results showed that the selected Iranian weightlifter, which belongs to the Caucasian race group, has potential genetics in endurance abilities as well as strength / power, likely. |
| first_indexed | 2024-04-11T05:59:49Z |
| format | Article |
| id | doaj.art-7c7695ea96a54b32bed93c79e046460f |
| institution | Directory Open Access Journal |
| issn | 1563-4728 2588-3135 |
| language | fas |
| last_indexed | 2024-04-11T05:59:49Z |
| publishDate | 2022-08-01 |
| publisher | Ilam University of Medical Sciences |
| record_format | Article |
| series | Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām |
| spelling | doaj.art-7c7695ea96a54b32bed93c79e046460f2022-12-22T04:41:43ZfasIlam University of Medical SciencesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām1563-47282588-31352022-08-01303112122Frequency and Association of SNP rs 8111989 in CKMM A/G Gene in Weightlifting Men with Non-Athlete MenFateme Hashemzade ghodaneh0Mohammad Reza Batavani1Mohsen Ghofrani2 Dept of Exercise Physiology, Faculty of Educational Sciences and Psychology, Sistan and Baluchestan University, Zahedan, Iran Center of Physical Education, Isfahan University of Technology, Isfahan 84156-83111, Iran Dept of Exercise Physiology, Faculty of Educational Sciences and Psychology, Sistan and Baluchestan University, Zahedan, Iran Introduction: Genetic factors affect physical performance, exercise response, as well as elite athletic status; Therefore, the aim of the present study was the investigation of the Frequency and association of SNP rs 8111989 in CKMM A/G gene in weightlifting men with non-athlete men. Material & Methods: In this descriptive study, the subjects were include of all (n=30) elite male weightlifters (league champions, members of national team, and the champions of Asian, world and Olympics) from Isfahan province, age: 21.77±7.11; Height: 179.87±6.98 and weight: 96.87±22.73 (mean±standard deviation) Which compared with 44 non-athletes with similar anthropometric (age, height and weight) characteristics. 4 cc saliva samples were collected from each subject and After DNA extraction, the allelic and genotypic prevalence of CKMM A/G gene was determined by PCR via RFLP and electrophoresis. Independent t-test, chi-square and logistic regression were used to analyze the data via the SPSS software version 20. Also the significance level was considered at P<0.05. Findings: The results showed that the prevalence of AG genotype was significantly higher than AA and GG genotypes in weightlifting, non-athlete and total population groups (P <0.05). Also, there was no significant relationship between CKMM A/G genotype and weightlifting status and there was no significant difference between weightlifters and non-athletes (P >0.05). Discussion & Conclusion: The results showed that the selected Iranian weightlifter, which belongs to the Caucasian race group, has potential genetics in endurance abilities as well as strength / power, likely.http://sjimu.medilam.ac.ir/article-1-7441-en.htmlsingle nucleotide polymorphismsport genomicelite male weightliftersnon-athletes |
| spellingShingle | Fateme Hashemzade ghodaneh Mohammad Reza Batavani Mohsen Ghofrani Frequency and Association of SNP rs 8111989 in CKMM A/G Gene in Weightlifting Men with Non-Athlete Men Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām single nucleotide polymorphism sport genomic elite male weightlifters non-athletes |
| title | Frequency and Association of SNP rs 8111989 in CKMM A/G Gene in Weightlifting Men with Non-Athlete Men |
| title_full | Frequency and Association of SNP rs 8111989 in CKMM A/G Gene in Weightlifting Men with Non-Athlete Men |
| title_fullStr | Frequency and Association of SNP rs 8111989 in CKMM A/G Gene in Weightlifting Men with Non-Athlete Men |
| title_full_unstemmed | Frequency and Association of SNP rs 8111989 in CKMM A/G Gene in Weightlifting Men with Non-Athlete Men |
| title_short | Frequency and Association of SNP rs 8111989 in CKMM A/G Gene in Weightlifting Men with Non-Athlete Men |
| title_sort | frequency and association of snp rs 8111989 in ckmm a g gene in weightlifting men with non athlete men |
| topic | single nucleotide polymorphism sport genomic elite male weightlifters non-athletes |
| url | http://sjimu.medilam.ac.ir/article-1-7441-en.html |
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