Case Report: Novel Biallelic Mutations in ARMC4 Cause Primary Ciliary Dyskinesia and Male Infertility in a Chinese Family

Case Report: Novel Biallelic Mutations in ARMC4 Cause Primary Ciliary Dyskinesia and Male Infertility in a Chinese Family

Primary ciliary dyskinesia (PCD) is a clinically and genetically heterogeneous ciliopathy affecting the cilia and sperm flagella. Mutations in genes related to the structural and functional defects of respiratory ciliary axoneme have been reported to be the predominant cause of this symptom; however...

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Bibliographic Details
Main Authors: Yang Gao, Chuan Xu, Qing Tan, Qunshan Shen, Huan Wu, Mingrong Lv, Kuokuo Li, Dongdong Tang, Bing Song, Yuping Xu, Ping Zhou, Zhaolian Wei, Fangbiao Tao, Yunxia Cao, Xiaojin He
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Genetics
Subjects:
male infertility
primary ciliary dyskinesia (Kartagener syndrome)
ARMC4
oligoasthenoterazoospermia
ICSI
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.715339/full

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