Educational disparities in Brazil may interfere with the cognitive performance of Parkinson's disease patients
ABSTRACT. The prevalence of cognitive impairment in Parkinson's disease (PD) is about 20% to 60%. The Mini-Mental Status Examination (MMSE) is the most used cognitive screening test. Objective: To evaluate the influence of clinical and demographic characteristics, specifically the education le...
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| Format: | Article |
| Language: | English |
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Associação Neurologia Cognitiva e do Comportamento
2023-11-01
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| Series: | Dementia & Neuropsychologia |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642023000100323&lng=en&tlng=en |
| _version_ | 1827698560615841792 |
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| author | Danielle Pessoa Lima Janine de Carvalho Bonfadini Alexandre Henrique Silva Carneiro Samuel Brito de Almeida Antonio Brazil Viana Júnior Ana Cecília Nogueira e Silva Jarbas de Sá Roriz Filho Pedro Braga Neto |
| author_facet | Danielle Pessoa Lima Janine de Carvalho Bonfadini Alexandre Henrique Silva Carneiro Samuel Brito de Almeida Antonio Brazil Viana Júnior Ana Cecília Nogueira e Silva Jarbas de Sá Roriz Filho Pedro Braga Neto |
| author_sort | Danielle Pessoa Lima |
| collection | DOAJ |
| description | ABSTRACT. The prevalence of cognitive impairment in Parkinson's disease (PD) is about 20% to 60%. The Mini-Mental Status Examination (MMSE) is the most used cognitive screening test. Objective: To evaluate the influence of clinical and demographic characteristics, specifically the education level, on the MMSE score in PD patients of a northeast Brazilian sample. Methods: We performed a cross-sectional study of 198 PD patients at a Movement Disorders outpatient clinic in Fortaleza, CE, Brazil. Participants were assessed by detailed clinical history, modified Hoehn and Yahr staging (HY), geriatric depression scale (GDS) and MMSE. Results: We found that 68% of patients had MMSE scores below the Brazilian thresholds, which were based in Brucki et al. study (2003). There was a statistically significant difference in the bivariate analysis between educational level and cut-off classification for MMSE. More years of formal schooling were associated with more patients scoring below threshold. We found that 75%, 68.8%, and 79.7% of individuals with more than 11, 9 to 11, and 4 to 8 years of formal schooling, respectively, were below the suggested Brazilian Brucki's threshold. GDS and age were negatively correlated with total MMSE and all its domains. There was no correlation between disease duration and MMSE. Subjects with hallucinations had lower scores. Conclusion: Most of the sample had lower performance according to Brazilian thresholds, but there was no control group and no neuropsychological test in this study. Further studies in northeast Brazil are needed to review MMSE cut-off values. |
| first_indexed | 2024-03-10T13:33:00Z |
| format | Article |
| id | doaj.art-7c8a80152def486e908b2d05d9708b99 |
| institution | Directory Open Access Journal |
| issn | 1980-5764 |
| language | English |
| last_indexed | 2024-03-10T13:33:00Z |
| publishDate | 2023-11-01 |
| publisher | Associação Neurologia Cognitiva e do Comportamento |
| record_format | Article |
| series | Dementia & Neuropsychologia |
| spelling | doaj.art-7c8a80152def486e908b2d05d9708b992023-11-21T07:46:12ZengAssociação Neurologia Cognitiva e do ComportamentoDementia & Neuropsychologia1980-57642023-11-011710.1590/1980-5764-dn-2022-0084Educational disparities in Brazil may interfere with the cognitive performance of Parkinson's disease patientsDanielle Pessoa Limahttps://orcid.org/0000-0003-4591-727XJanine de Carvalho Bonfadinihttps://orcid.org/0000-0001-9789-8459Alexandre Henrique Silva Carneirohttps://orcid.org/0000-0001-9658-4730Samuel Brito de Almeidahttps://orcid.org/0000-0001-6174-1839Antonio Brazil Viana Júniorhttps://orcid.org/0000-0001-6608-3134Ana Cecília Nogueira e Silvahttps://orcid.org/0000-0003-0686-6684Jarbas de Sá Roriz Filhohttps://orcid.org/0000-0002-5928-0399Pedro Braga Netohttps://orcid.org/0000-0001-9186-9243ABSTRACT. The prevalence of cognitive impairment in Parkinson's disease (PD) is about 20% to 60%. The Mini-Mental Status Examination (MMSE) is the most used cognitive screening test. Objective: To evaluate the influence of clinical and demographic characteristics, specifically the education level, on the MMSE score in PD patients of a northeast Brazilian sample. Methods: We performed a cross-sectional study of 198 PD patients at a Movement Disorders outpatient clinic in Fortaleza, CE, Brazil. Participants were assessed by detailed clinical history, modified Hoehn and Yahr staging (HY), geriatric depression scale (GDS) and MMSE. Results: We found that 68% of patients had MMSE scores below the Brazilian thresholds, which were based in Brucki et al. study (2003). There was a statistically significant difference in the bivariate analysis between educational level and cut-off classification for MMSE. More years of formal schooling were associated with more patients scoring below threshold. We found that 75%, 68.8%, and 79.7% of individuals with more than 11, 9 to 11, and 4 to 8 years of formal schooling, respectively, were below the suggested Brazilian Brucki's threshold. GDS and age were negatively correlated with total MMSE and all its domains. There was no correlation between disease duration and MMSE. Subjects with hallucinations had lower scores. Conclusion: Most of the sample had lower performance according to Brazilian thresholds, but there was no control group and no neuropsychological test in this study. Further studies in northeast Brazil are needed to review MMSE cut-off values.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642023000100323&lng=en&tlng=enParkinson DiseaseCognitive DysfunctionMental Status and Dementia Tests |
| spellingShingle | Danielle Pessoa Lima Janine de Carvalho Bonfadini Alexandre Henrique Silva Carneiro Samuel Brito de Almeida Antonio Brazil Viana Júnior Ana Cecília Nogueira e Silva Jarbas de Sá Roriz Filho Pedro Braga Neto Educational disparities in Brazil may interfere with the cognitive performance of Parkinson's disease patients Dementia & Neuropsychologia Parkinson Disease Cognitive Dysfunction Mental Status and Dementia Tests |
| title | Educational disparities in Brazil may interfere with the cognitive performance of Parkinson's disease patients |
| title_full | Educational disparities in Brazil may interfere with the cognitive performance of Parkinson's disease patients |
| title_fullStr | Educational disparities in Brazil may interfere with the cognitive performance of Parkinson's disease patients |
| title_full_unstemmed | Educational disparities in Brazil may interfere with the cognitive performance of Parkinson's disease patients |
| title_short | Educational disparities in Brazil may interfere with the cognitive performance of Parkinson's disease patients |
| title_sort | educational disparities in brazil may interfere with the cognitive performance of parkinson s disease patients |
| topic | Parkinson Disease Cognitive Dysfunction Mental Status and Dementia Tests |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642023000100323&lng=en&tlng=en |
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