Hippocampal gray matter volume alterations in patients with first-episode and recurrent major depressive disorder and their associations with gene profiles

Hippocampal gray matter volume alterations in patients with first-episode and recurrent major depressive disorder and their associations with gene profiles

Abstract Background Recent studies indicate that patients with first-episode drug-naïve (FEDN) and recurrent major depressive disorder (R-MDD) exhibit distinct atrophy patterns in the hippocampal subregions along the proximal-distal axis. However, it remains unclear whether such differences occur al...

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Bibliographic Details
Main Authors: Fenfen Sun, Yifan Shuai, Jingru Wang, Jin Yan, Bin Lin, Xinyun Li, Zhiyong Zhao
Format: Article
Language:English
Published: BMC 2025-02-01
Series:BMC Psychiatry
Subjects:
Major depressive disorder
Hippocampal subfields
Magnetic resonance imaging
Gray matter volume
Gene expression
Online Access:https://doi.org/10.1186/s12888-025-06562-4

Internet

https://doi.org/10.1186/s12888-025-06562-4

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