Perioperative adverse events in adult and pediatric spine surgery: A prospective cohort analysis of 364 consecutive patients
Introduction: A precise knowledge of the possible Adverse Events (AEs) related to spinal surgical procedures is crucial in clinical practice. Research Question: Purposes of this study are: to determine the prevalence and severity of perioperative AEs associated with pediatric and adult spine surgery...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2022-01-01
|
Series: | Brain and Spine |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2772529421008584 |
_version_ | 1797977748541538304 |
---|---|
author | Alessio Lovi Enrico Gallazzi Fabio Galbusera Alessandra Colombini Fabrizio Pregliasco Giuseppe Peretti Marco Brayda-Bruno |
author_facet | Alessio Lovi Enrico Gallazzi Fabio Galbusera Alessandra Colombini Fabrizio Pregliasco Giuseppe Peretti Marco Brayda-Bruno |
author_sort | Alessio Lovi |
collection | DOAJ |
description | Introduction: A precise knowledge of the possible Adverse Events (AEs) related to spinal surgical procedures is crucial in clinical practice. Research Question: Purposes of this study are: to determine the prevalence and severity of perioperative AEs associated with pediatric and adult spine surgery in a high volume center; to estimate the impact of perioperative AEs on length of hospital stay (LOS). Material and Methods: This is a prospective, observational, monocenter study, including 346 consecutive patients (294 adults and 52 pediatrics). The SAVES-V2 questionnaire was used to record AEs. The form was updated by the medical staff every time an adverse event was recorded during hospitalization. Results: 21,2% of pediatric patients and 20,7% of adults had at least 1 perioperative AEs. In adults, dural tear (3.1%) and neuropathic pain (4,8%), were the most frequent intraoperative and postoperative AE, respectively. In pediatric patients, neurologic deterioration was the most frequent postoperative AE. A diagnosis of deformity (p=0.01), an ASA grade equal or superior to 3 (p=0.023) and the procedure ‘Posterior Spinal Fusion’ (p=0.001) were associated with a higher frequency of AEs. AEs required prolonged LOS in 40 cases, 7 (70%) pediatric patients and 33 (65%) adults. Discussion and Conclusion: The overall prevalence of AEs is 20.8%, and, although the distribution is almost equal between adult and pediatric patients, their severity is related to age, being higher in pediatric patients. Deformities, deformity correction, revision surgery and AP surgery are the most impactful factors. AEs seriously affect hospitalization, with prolonged LOS (mean 6 days). |
first_indexed | 2024-04-11T05:11:56Z |
format | Article |
id | doaj.art-7c91ce7191134bc2b5fc788da932e344 |
institution | Directory Open Access Journal |
issn | 2772-5294 |
language | English |
last_indexed | 2024-04-11T05:11:56Z |
publishDate | 2022-01-01 |
publisher | Elsevier |
record_format | Article |
series | Brain and Spine |
spelling | doaj.art-7c91ce7191134bc2b5fc788da932e3442022-12-25T04:19:54ZengElsevierBrain and Spine2772-52942022-01-012100858Perioperative adverse events in adult and pediatric spine surgery: A prospective cohort analysis of 364 consecutive patientsAlessio Lovi0Enrico Gallazzi1Fabio Galbusera2Alessandra Colombini3Fabrizio Pregliasco4Giuseppe Peretti5Marco Brayda-Bruno6Spine Surgery III – Scoliosis Division, I.R.C.C.S. Istituto Ortopedico Galeazzi, Milan, ItalyU.O. Ortopedia e Traumatologia per le Patologie della Colonna Vertebrale, ASST Centro Specialistico Ortopedico Traumatologico G. Pini – CTO, Milan, Italy; Corresponding author.I.R.C.C.S. Istituto Ortopedico Galeazzi, Milan, ItalyOrthopaedic Biotechnology Lab, IRCCS Istituto Ortopedico Galeazzi, Milan, ItalyI.R.C.C.S. Istituto Ortopedico Galeazzi, Milan, ItalyI.R.C.C.S. Istituto Ortopedico Galeazzi, Milan, ItalySpine Surgery III – Scoliosis Division, I.R.C.C.S. Istituto Ortopedico Galeazzi, Milan, ItalyIntroduction: A precise knowledge of the possible Adverse Events (AEs) related to spinal surgical procedures is crucial in clinical practice. Research Question: Purposes of this study are: to determine the prevalence and severity of perioperative AEs associated with pediatric and adult spine surgery in a high volume center; to estimate the impact of perioperative AEs on length of hospital stay (LOS). Material and Methods: This is a prospective, observational, monocenter study, including 346 consecutive patients (294 adults and 52 pediatrics). The SAVES-V2 questionnaire was used to record AEs. The form was updated by the medical staff every time an adverse event was recorded during hospitalization. Results: 21,2% of pediatric patients and 20,7% of adults had at least 1 perioperative AEs. In adults, dural tear (3.1%) and neuropathic pain (4,8%), were the most frequent intraoperative and postoperative AE, respectively. In pediatric patients, neurologic deterioration was the most frequent postoperative AE. A diagnosis of deformity (p=0.01), an ASA grade equal or superior to 3 (p=0.023) and the procedure ‘Posterior Spinal Fusion’ (p=0.001) were associated with a higher frequency of AEs. AEs required prolonged LOS in 40 cases, 7 (70%) pediatric patients and 33 (65%) adults. Discussion and Conclusion: The overall prevalence of AEs is 20.8%, and, although the distribution is almost equal between adult and pediatric patients, their severity is related to age, being higher in pediatric patients. Deformities, deformity correction, revision surgery and AP surgery are the most impactful factors. AEs seriously affect hospitalization, with prolonged LOS (mean 6 days).http://www.sciencedirect.com/science/article/pii/S2772529421008584Spine surgeryAdverse eventsEpidemiologyPatient's SafetyDeformity |
spellingShingle | Alessio Lovi Enrico Gallazzi Fabio Galbusera Alessandra Colombini Fabrizio Pregliasco Giuseppe Peretti Marco Brayda-Bruno Perioperative adverse events in adult and pediatric spine surgery: A prospective cohort analysis of 364 consecutive patients Brain and Spine Spine surgery Adverse events Epidemiology Patient's Safety Deformity |
title | Perioperative adverse events in adult and pediatric spine surgery: A prospective cohort analysis of 364 consecutive patients |
title_full | Perioperative adverse events in adult and pediatric spine surgery: A prospective cohort analysis of 364 consecutive patients |
title_fullStr | Perioperative adverse events in adult and pediatric spine surgery: A prospective cohort analysis of 364 consecutive patients |
title_full_unstemmed | Perioperative adverse events in adult and pediatric spine surgery: A prospective cohort analysis of 364 consecutive patients |
title_short | Perioperative adverse events in adult and pediatric spine surgery: A prospective cohort analysis of 364 consecutive patients |
title_sort | perioperative adverse events in adult and pediatric spine surgery a prospective cohort analysis of 364 consecutive patients |
topic | Spine surgery Adverse events Epidemiology Patient's Safety Deformity |
url | http://www.sciencedirect.com/science/article/pii/S2772529421008584 |
work_keys_str_mv | AT alessiolovi perioperativeadverseeventsinadultandpediatricspinesurgeryaprospectivecohortanalysisof364consecutivepatients AT enricogallazzi perioperativeadverseeventsinadultandpediatricspinesurgeryaprospectivecohortanalysisof364consecutivepatients AT fabiogalbusera perioperativeadverseeventsinadultandpediatricspinesurgeryaprospectivecohortanalysisof364consecutivepatients AT alessandracolombini perioperativeadverseeventsinadultandpediatricspinesurgeryaprospectivecohortanalysisof364consecutivepatients AT fabriziopregliasco perioperativeadverseeventsinadultandpediatricspinesurgeryaprospectivecohortanalysisof364consecutivepatients AT giuseppeperetti perioperativeadverseeventsinadultandpediatricspinesurgeryaprospectivecohortanalysisof364consecutivepatients AT marcobraydabruno perioperativeadverseeventsinadultandpediatricspinesurgeryaprospectivecohortanalysisof364consecutivepatients |