Migrasomes, new vescicles as Hansel and Gretel white pebbles?
Abstract Migrasomes, released by migrating cells, belong to the heterogeneous world of extracellular vesicles (EVs). However, they can be distinguished from all other members of EVs by their size, biorigin and protein cargo. As far as we know, they can play important roles in various communication p...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-04-01
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| Series: | Biology Direct |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13062-022-00321-1 |
| _version_ | 1811289687961108480 |
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| author | Arianna Di Daniele Ylenia Antonucci Silvia Campello |
| author_facet | Arianna Di Daniele Ylenia Antonucci Silvia Campello |
| author_sort | Arianna Di Daniele |
| collection | DOAJ |
| description | Abstract Migrasomes, released by migrating cells, belong to the heterogeneous world of extracellular vesicles (EVs). However, they can be distinguished from all other members of EVs by their size, biorigin and protein cargo. As far as we know, they can play important roles in various communication processes, by mediating the release of signals, such as mRNAs, proteins or damaged mitochondria. To extend and better understand the functional roles and importance of migrasomes, it is first essential to well understand the basic molecular mechanisms behind their formation and function. Herein, we endeavor to provide a brief and up-to-date description of migrasome biogenesis, release, characterization, biological properties and functional activities in cell-to-cell communication, and we will discuss and propose putative new functions for these vesicles. |
| first_indexed | 2024-04-13T03:58:48Z |
| format | Article |
| id | doaj.art-7c9d5cb204a54d649035a164f63b83eb |
| institution | Directory Open Access Journal |
| issn | 1745-6150 |
| language | English |
| last_indexed | 2024-04-13T03:58:48Z |
| publishDate | 2022-04-01 |
| publisher | BMC |
| record_format | Article |
| series | Biology Direct |
| spelling | doaj.art-7c9d5cb204a54d649035a164f63b83eb2022-12-22T03:03:32ZengBMCBiology Direct1745-61502022-04-011711910.1186/s13062-022-00321-1Migrasomes, new vescicles as Hansel and Gretel white pebbles?Arianna Di Daniele0Ylenia Antonucci1Silvia Campello2Department of Biology, University of Rome “Tor Vergata”Department of Biology, University of Rome “Tor Vergata”Department of Biology, University of Rome “Tor Vergata”Abstract Migrasomes, released by migrating cells, belong to the heterogeneous world of extracellular vesicles (EVs). However, they can be distinguished from all other members of EVs by their size, biorigin and protein cargo. As far as we know, they can play important roles in various communication processes, by mediating the release of signals, such as mRNAs, proteins or damaged mitochondria. To extend and better understand the functional roles and importance of migrasomes, it is first essential to well understand the basic molecular mechanisms behind their formation and function. Herein, we endeavor to provide a brief and up-to-date description of migrasome biogenesis, release, characterization, biological properties and functional activities in cell-to-cell communication, and we will discuss and propose putative new functions for these vesicles.https://doi.org/10.1186/s13062-022-00321-1MigrasomeCell migrationCommunicationSignallingExtracellular vesicles |
| spellingShingle | Arianna Di Daniele Ylenia Antonucci Silvia Campello Migrasomes, new vescicles as Hansel and Gretel white pebbles? Biology Direct Migrasome Cell migration Communication Signalling Extracellular vesicles |
| title | Migrasomes, new vescicles as Hansel and Gretel white pebbles? |
| title_full | Migrasomes, new vescicles as Hansel and Gretel white pebbles? |
| title_fullStr | Migrasomes, new vescicles as Hansel and Gretel white pebbles? |
| title_full_unstemmed | Migrasomes, new vescicles as Hansel and Gretel white pebbles? |
| title_short | Migrasomes, new vescicles as Hansel and Gretel white pebbles? |
| title_sort | migrasomes new vescicles as hansel and gretel white pebbles |
| topic | Migrasome Cell migration Communication Signalling Extracellular vesicles |
| url | https://doi.org/10.1186/s13062-022-00321-1 |
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