Factors influencing adherence to anti-retroviral therapy in amazonian indigenous people living with HIV/AIDS
Abstract Background Indigenous communities in Peru has been historically affected by high mortality rates attributable to HIV-AIDS infection, associated with a low access to health services, and socio-cultural barriers. In this context, the study aimed to describe factors associated with antiretrovi...
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| Format: | Article |
| Language: | English |
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BMC
2023-03-01
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| Series: | BMC Public Health |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12889-023-15362-y |
| _version_ | 1827982496897171456 |
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| author | Félix Valenzuela-Oré Yolanda Angulo-Bazán Lucy D. Lazóriga-Sandoval Norma L. Cruz-Vilcarromero Cecilia R. Cubas-Sagardia |
| author_facet | Félix Valenzuela-Oré Yolanda Angulo-Bazán Lucy D. Lazóriga-Sandoval Norma L. Cruz-Vilcarromero Cecilia R. Cubas-Sagardia |
| author_sort | Félix Valenzuela-Oré |
| collection | DOAJ |
| description | Abstract Background Indigenous communities in Peru has been historically affected by high mortality rates attributable to HIV-AIDS infection, associated with a low access to health services, and socio-cultural barriers. In this context, the study aimed to describe factors associated with antiretroviral treatment adherence in people from Awajun and Wampis indigenous communities, living with HIV-AIDS in a Peruvian Amazonian region. Methods A cross-sectional study was completed with a consecutive sample of people from indigenous communities (Awajun or Wampis) living with HIV, who were receiving antiretroviral treatment for at least the last three months. Participants were recruited between October 1 and December 30, 2021, from four districts of Bagua and Condorcanqui provinces in the Amazonian region. An ad-hoc questionnaire was used to collect information about demographic, economic, and socio-cultural factors and access to health services. The Simplified Medication Adherence Questionnaire (SMAQ) was used to evaluate adherence to antiretroviral therapy. Multivariate logistic regression analysis with backward stepwise was performed to explore factors that might influence adherence. Results Of the 208 participants, 28.8% reported complete adherence to antiretroviral treatment. The multivariate logistic regression showed that occupation (aPR: 1.86; 95%CI 1.15–3.02), economic income (aPR: 0.64; 95%CI 0.41–0.99), and adverse reactions to antiretroviral therapy (aPR: 0.36; 95%CI 0.18–0.70) were related to complete adherence to medication. Conclusion Only a third of participants reported complete adherence to antiretroviral therapy. Factors associated with adherence to antiretroviral medication were related to socioeconomic conditions and adverse reactions to the therapeutic scheme. Interventions to improve adherence in indigenous people living with HIV should consider these factors in order to develop effective implementation strategies. |
| first_indexed | 2024-04-09T22:33:58Z |
| format | Article |
| id | doaj.art-7c9f003ec0894ba2ad529862fe6df2e1 |
| institution | Directory Open Access Journal |
| issn | 1471-2458 |
| language | English |
| last_indexed | 2024-04-09T22:33:58Z |
| publishDate | 2023-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Public Health |
| spelling | doaj.art-7c9f003ec0894ba2ad529862fe6df2e12023-03-22T12:35:11ZengBMCBMC Public Health1471-24582023-03-0123111010.1186/s12889-023-15362-yFactors influencing adherence to anti-retroviral therapy in amazonian indigenous people living with HIV/AIDSFélix Valenzuela-Oré0Yolanda Angulo-Bazán1Lucy D. Lazóriga-Sandoval2Norma L. Cruz-Vilcarromero3Cecilia R. Cubas-Sagardia4Centro Nacional de Salud InterculturalCentro Nacional de Salud InterculturalCentro Nacional de Salud InterculturalDirección Regional de Salud AmazonasDirección Regional de Salud AmazonasAbstract Background Indigenous communities in Peru has been historically affected by high mortality rates attributable to HIV-AIDS infection, associated with a low access to health services, and socio-cultural barriers. In this context, the study aimed to describe factors associated with antiretroviral treatment adherence in people from Awajun and Wampis indigenous communities, living with HIV-AIDS in a Peruvian Amazonian region. Methods A cross-sectional study was completed with a consecutive sample of people from indigenous communities (Awajun or Wampis) living with HIV, who were receiving antiretroviral treatment for at least the last three months. Participants were recruited between October 1 and December 30, 2021, from four districts of Bagua and Condorcanqui provinces in the Amazonian region. An ad-hoc questionnaire was used to collect information about demographic, economic, and socio-cultural factors and access to health services. The Simplified Medication Adherence Questionnaire (SMAQ) was used to evaluate adherence to antiretroviral therapy. Multivariate logistic regression analysis with backward stepwise was performed to explore factors that might influence adherence. Results Of the 208 participants, 28.8% reported complete adherence to antiretroviral treatment. The multivariate logistic regression showed that occupation (aPR: 1.86; 95%CI 1.15–3.02), economic income (aPR: 0.64; 95%CI 0.41–0.99), and adverse reactions to antiretroviral therapy (aPR: 0.36; 95%CI 0.18–0.70) were related to complete adherence to medication. Conclusion Only a third of participants reported complete adherence to antiretroviral therapy. Factors associated with adherence to antiretroviral medication were related to socioeconomic conditions and adverse reactions to the therapeutic scheme. Interventions to improve adherence in indigenous people living with HIV should consider these factors in order to develop effective implementation strategies.https://doi.org/10.1186/s12889-023-15362-yAdherenceHIV-AIDSIndigenous populations |
| spellingShingle | Félix Valenzuela-Oré Yolanda Angulo-Bazán Lucy D. Lazóriga-Sandoval Norma L. Cruz-Vilcarromero Cecilia R. Cubas-Sagardia Factors influencing adherence to anti-retroviral therapy in amazonian indigenous people living with HIV/AIDS BMC Public Health Adherence HIV-AIDS Indigenous populations |
| title | Factors influencing adherence to anti-retroviral therapy in amazonian indigenous people living with HIV/AIDS |
| title_full | Factors influencing adherence to anti-retroviral therapy in amazonian indigenous people living with HIV/AIDS |
| title_fullStr | Factors influencing adherence to anti-retroviral therapy in amazonian indigenous people living with HIV/AIDS |
| title_full_unstemmed | Factors influencing adherence to anti-retroviral therapy in amazonian indigenous people living with HIV/AIDS |
| title_short | Factors influencing adherence to anti-retroviral therapy in amazonian indigenous people living with HIV/AIDS |
| title_sort | factors influencing adherence to anti retroviral therapy in amazonian indigenous people living with hiv aids |
| topic | Adherence HIV-AIDS Indigenous populations |
| url | https://doi.org/10.1186/s12889-023-15362-y |
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