Genetic Data Showing Evolutionary Links between Leishmania and Endotrypanum
Striking similarities at the morphological, molecular and biological levels exist between many trypanosomatids isolated from sylvatic insects and/or vertebrate reservoir hosts that make the identification of medically important parasites demanding. Some molecular data have pointed to the relationshi...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Fundação Oswaldo Cruz (FIOCRUZ)
1998-09-01
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| Series: | Memorias do Instituto Oswaldo Cruz |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761998000500020 |
| _version_ | 1797757193304408064 |
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| author | Elisa Cupolillo Luiza OR Pereira Octávio Fernandes Marcos P Catanho Júlio C Pereira Enrique Medina-Acosta Gabriel Grimaldi Jr |
| author_facet | Elisa Cupolillo Luiza OR Pereira Octávio Fernandes Marcos P Catanho Júlio C Pereira Enrique Medina-Acosta Gabriel Grimaldi Jr |
| author_sort | Elisa Cupolillo |
| collection | DOAJ |
| description | Striking similarities at the morphological, molecular and biological levels exist between many trypanosomatids isolated from sylvatic insects and/or vertebrate reservoir hosts that make the identification of medically important parasites demanding. Some molecular data have pointed to the relationship between some Leishmania species and Endotrypanum, which has an important epidemiological significance and can be helpful to understand the evolution of those parasites. In this study, we have demonstrated a close genetic relationship between Endotrypanum and two new leishmanial species, L. (V.) colombiensis and L. (V.) equatorensis. We have used (a) numerical zymotaxonomy and (b) the variability of the internal transcribed spacers of the rRNA genes to examine relationships in this group. The evolutionary trees obtained revealed high genetic similarity between L. (V.) colombiensis, L. (V.) equatorensis and Endotrypanum, forming a tight cluster of parasites. Based on further results of (c) minicircle kDNA heterogeneity analysis and (d) measurement of the sialidase activity these parasites were also grouped together. |
| first_indexed | 2024-03-12T18:12:25Z |
| format | Article |
| id | doaj.art-7c9f13d0f6ad4b6ca76ba0b0f99cd1b5 |
| institution | Directory Open Access Journal |
| issn | 0074-0276 1678-8060 |
| language | English |
| last_indexed | 2024-03-12T18:12:25Z |
| publishDate | 1998-09-01 |
| publisher | Fundação Oswaldo Cruz (FIOCRUZ) |
| record_format | Article |
| series | Memorias do Instituto Oswaldo Cruz |
| spelling | doaj.art-7c9f13d0f6ad4b6ca76ba0b0f99cd1b52023-08-02T09:15:07ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz0074-02761678-80601998-09-0193567710.1590/S0074-02761998000500020Genetic Data Showing Evolutionary Links between Leishmania and EndotrypanumElisa CupolilloLuiza OR PereiraOctávio FernandesMarcos P CatanhoJúlio C PereiraEnrique Medina-AcostaGabriel Grimaldi JrStriking similarities at the morphological, molecular and biological levels exist between many trypanosomatids isolated from sylvatic insects and/or vertebrate reservoir hosts that make the identification of medically important parasites demanding. Some molecular data have pointed to the relationship between some Leishmania species and Endotrypanum, which has an important epidemiological significance and can be helpful to understand the evolution of those parasites. In this study, we have demonstrated a close genetic relationship between Endotrypanum and two new leishmanial species, L. (V.) colombiensis and L. (V.) equatorensis. We have used (a) numerical zymotaxonomy and (b) the variability of the internal transcribed spacers of the rRNA genes to examine relationships in this group. The evolutionary trees obtained revealed high genetic similarity between L. (V.) colombiensis, L. (V.) equatorensis and Endotrypanum, forming a tight cluster of parasites. Based on further results of (c) minicircle kDNA heterogeneity analysis and (d) measurement of the sialidase activity these parasites were also grouped together.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761998000500020Leishmania colombiensisLeishmania equatorensisEndotrypanummultilocus enzyme electrophoresismolecular characterizationnumerical analysissialidase activitykDNA |
| spellingShingle | Elisa Cupolillo Luiza OR Pereira Octávio Fernandes Marcos P Catanho Júlio C Pereira Enrique Medina-Acosta Gabriel Grimaldi Jr Genetic Data Showing Evolutionary Links between Leishmania and Endotrypanum Memorias do Instituto Oswaldo Cruz Leishmania colombiensis Leishmania equatorensis Endotrypanum multilocus enzyme electrophoresis molecular characterization numerical analysis sialidase activity kDNA |
| title | Genetic Data Showing Evolutionary Links between Leishmania and Endotrypanum |
| title_full | Genetic Data Showing Evolutionary Links between Leishmania and Endotrypanum |
| title_fullStr | Genetic Data Showing Evolutionary Links between Leishmania and Endotrypanum |
| title_full_unstemmed | Genetic Data Showing Evolutionary Links between Leishmania and Endotrypanum |
| title_short | Genetic Data Showing Evolutionary Links between Leishmania and Endotrypanum |
| title_sort | genetic data showing evolutionary links between leishmania and endotrypanum |
| topic | Leishmania colombiensis Leishmania equatorensis Endotrypanum multilocus enzyme electrophoresis molecular characterization numerical analysis sialidase activity kDNA |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761998000500020 |
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