Research Progress on Benzimidazole Fungicides: A Review

Benzimidazole fungicides are a class of highly effective, low-toxicity, systemic broad-spectrum fungicides developed in the 1960s and 1970s, based on the fungicidal activity of the benzimidazole ring structure. They exhibit biological activities including anticancer, antibacterial, and antiparasitic...

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Main Authors: Song Bai, Miaohe Zhang, Shouying Tang, Miao Li, Rong Wu, Suran Wan, Lijun Chen, Xian Wei, Feifei Li
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/29/6/1218
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author Song Bai
Miaohe Zhang
Shouying Tang
Miao Li
Rong Wu
Suran Wan
Lijun Chen
Xian Wei
Feifei Li
author_facet Song Bai
Miaohe Zhang
Shouying Tang
Miao Li
Rong Wu
Suran Wan
Lijun Chen
Xian Wei
Feifei Li
author_sort Song Bai
collection DOAJ
description Benzimidazole fungicides are a class of highly effective, low-toxicity, systemic broad-spectrum fungicides developed in the 1960s and 1970s, based on the fungicidal activity of the benzimidazole ring structure. They exhibit biological activities including anticancer, antibacterial, and antiparasitic effects. Due to their particularly outstanding antibacterial properties, they are widely used in agriculture to prevent and control various plant diseases caused by fungi. The main products of benzimidazole fungicides include benomyl, carbendazim, thiabendazole, albendazole, thiophanate, thiophanate-methyl, fuberidazole, methyl (1-{[(5-cyanopentyl)amino]carbonyl}-1<i>H</i>-benzimidazol-2-yl) carbamate, and carbendazim salicylate. This article mainly reviews the physicochemical properties, toxicological properties, disease control efficacy, and pesticide residue and detection technologies of the aforementioned nine benzimidazole fungicides and their main metabolite (2-aminobenzimidazole). On this basis, a brief outlook on the future research directions of benzimidazole fungicides is presented.
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spelling doaj.art-7ca35691b8564246afcd05257fb24ff02024-03-27T13:56:46ZengMDPI AGMolecules1420-30492024-03-01296121810.3390/molecules29061218Research Progress on Benzimidazole Fungicides: A ReviewSong Bai0Miaohe Zhang1Shouying Tang2Miao Li3Rong Wu4Suran Wan5Lijun Chen6Xian Wei7Feifei Li8Guizhou Industry Polytechnic College, Guiyang 550008, ChinaSchool of Chemical Engineering, Guizhou Institute of Technology, Guiyang 550003, ChinaGuizhou Industry Polytechnic College, Guiyang 550008, ChinaGuizhou Industry Polytechnic College, Guiyang 550008, ChinaGuizhou Industry Polytechnic College, Guiyang 550008, ChinaGuizhou Industry Polytechnic College, Guiyang 550008, ChinaSchool of Chemical Engineering, Guizhou Institute of Technology, Guiyang 550003, ChinaSchool of Chemical Engineering, Guizhou Institute of Technology, Guiyang 550003, ChinaSchool of Chemical Engineering, Guizhou Institute of Technology, Guiyang 550003, ChinaBenzimidazole fungicides are a class of highly effective, low-toxicity, systemic broad-spectrum fungicides developed in the 1960s and 1970s, based on the fungicidal activity of the benzimidazole ring structure. They exhibit biological activities including anticancer, antibacterial, and antiparasitic effects. Due to their particularly outstanding antibacterial properties, they are widely used in agriculture to prevent and control various plant diseases caused by fungi. The main products of benzimidazole fungicides include benomyl, carbendazim, thiabendazole, albendazole, thiophanate, thiophanate-methyl, fuberidazole, methyl (1-{[(5-cyanopentyl)amino]carbonyl}-1<i>H</i>-benzimidazol-2-yl) carbamate, and carbendazim salicylate. This article mainly reviews the physicochemical properties, toxicological properties, disease control efficacy, and pesticide residue and detection technologies of the aforementioned nine benzimidazole fungicides and their main metabolite (2-aminobenzimidazole). On this basis, a brief outlook on the future research directions of benzimidazole fungicides is presented.https://www.mdpi.com/1420-3049/29/6/1218benzimidazole fungicidescarbendazimtoxicitydisease prevention and controldetermination methods
spellingShingle Song Bai
Miaohe Zhang
Shouying Tang
Miao Li
Rong Wu
Suran Wan
Lijun Chen
Xian Wei
Feifei Li
Research Progress on Benzimidazole Fungicides: A Review
Molecules
benzimidazole fungicides
carbendazim
toxicity
disease prevention and control
determination methods
title Research Progress on Benzimidazole Fungicides: A Review
title_full Research Progress on Benzimidazole Fungicides: A Review
title_fullStr Research Progress on Benzimidazole Fungicides: A Review
title_full_unstemmed Research Progress on Benzimidazole Fungicides: A Review
title_short Research Progress on Benzimidazole Fungicides: A Review
title_sort research progress on benzimidazole fungicides a review
topic benzimidazole fungicides
carbendazim
toxicity
disease prevention and control
determination methods
url https://www.mdpi.com/1420-3049/29/6/1218
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AT rongwu researchprogressonbenzimidazolefungicidesareview
AT suranwan researchprogressonbenzimidazolefungicidesareview
AT lijunchen researchprogressonbenzimidazolefungicidesareview
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