A molecular perspective on mGluR5 regulation in the antidepressant effect of ketamine
Ketamine, a non-competitive N-methyl-D-aspartate receptor (NMDAR) antagonist, has received much attention for its rapid antidepressant effects. A single administration of ketamine elicits rapid and sustained antidepressant effects in both humans and animals. Current efforts are focused on uncovering...
Auteurs principaux: | , |
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Format: | Article |
Langue: | English |
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Elsevier
2024-02-01
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Collection: | Pharmacological Research |
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Accès en ligne: | http://www.sciencedirect.com/science/article/pii/S1043661824000252 |